Association Between Vancomycin Minimum Inhibitory Concentration and Mortality Among Patients With Staphylococcus aureus Bloodstream Infections: A Systematic Review and Meta-analysis

IMPORTANCE: Staphylococcus aureus bacteremia (SAB) is a worldwide problem. It is unclear whether higher-vancomycin minimum inhibitory concentration (MIC) is associated with mortality. This potential association has direct consequences for patients and public health. DATA SOURCES: PubMed, Embase, the...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2014-10, Vol.312 (15), p.1552-1564
Hauptverfasser:	Kalil, Andre C, Van Schooneveld, Trevor C, Fey, Paul D, Rupp, Mark E
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Antibiotics Bacteremia - drug therapy Bacteremia - mortality Humans Meta-analysis Microbial Sensitivity Tests Mortality Staphylococcal Infections - drug therapy Staphylococcal Infections - mortality Staphylococcus aureus Staphylococcus infections Systematic review Vancomycin - pharmacology Vancomycin - therapeutic use Vancomycin Resistance
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