A Polymorphism in the Promoter Region of the Survivin Gene is Related to Hemorrhagic Transformation in Patients with Acute Ischemic Stroke

Hemorrhagic transformation (HT) of cerebral infarction is a common and serious occurrence following acute ischemic stroke. The expression of survivin, a member of the inhibitor of apoptosis protein family, has been shown to increase after cerebral ischemia. This protein has been mainly located at th...

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Veröffentlicht in:	Neuromolecular medicine 2014-12, Vol.16 (4), p.856-861
Hauptverfasser:	Mallolas, Judith, Rodríguez, Rocío, Gubern, Carme, Camós, Susanna, Serena, Joaquín, Castellanos, Mar
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alleles Biomedical and Life Sciences Biomedicine Blood-Brain Barrier Brain Ischemia - complications Case-Control Studies Cerebral Hemorrhage - epidemiology Cerebral Hemorrhage - etiology Cerebral Hemorrhage - genetics Cerebral Hemorrhage - pathology Cerebral Hemorrhage - physiopathology Cerebral Infarction - complications Comorbidity Diffusion Magnetic Resonance Imaging Female Genetic Predisposition to Disease Genotype Humans Inhibitor of Apoptosis Proteins - genetics Inhibitor of Apoptosis Proteins - physiology Internal Medicine Male Matrix Metalloproteinase 9 - blood Middle Aged Neurology Neurosciences Original Paper Phenotype Polymorphism, Single Nucleotide Polymorphism, Single-Stranded Conformational Promoter Regions, Genetic - genetics Risk Risk Factors Sequence Analysis, DNA Single-Blind Method Spain - epidemiology
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