Rapid purification method for vitamin A-derived aging pigments A2E and iso-A2E using cation exchange resin

▸ Cation exchange resin was utilized for the purification of aging pigments in the eye. ▸ A2E and iso-A2E were selectively purified by ion exchange extraction method. ▸ Easier and economic large scale purification of A2E and iso-A2E is developed. A2E, known to be involved in the pathogenesis of age-...

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Veröffentlicht in:	Journal of Chromatography A 2012-08, Vol.1251, p.232-235
Hauptverfasser:	Jee, Eun Hye, Kim, So Ra, Jang, Young Pyo
Format:	Artikel
Sprache:	eng
Schlagworte:	A2E Age-related macular degeneration Aging pigment biomimetic synthesis Cation exchange Cation Exchange Resins - chemistry Chromatography, High Pressure Liquid Chromatography, Ion Exchange - instrumentation Chromatography, Ion Exchange - methods cis-trans isomers Ethanolamine - chemistry eyes fluorescence high performance liquid chromatography macular degeneration Methanol pathogenesis pigments purification methods Pyridinium Compounds - chemistry Pyridinium Compounds - isolation & purification rapid methods Resins, Synthetic - chemistry Retinoids - chemistry Retinoids - isolation & purification Sodium Hydroxide Spectrophotometry, Ultraviolet Trifluoroacetic Acid Vitamin A - chemistry
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