Antihyperglycemic, antihyperlipidemic and antioxidant activities of polysaccharides from Catathelasma ventricosum in streptozotocin-induced diabetic mice

•CVPs have wide range of molecular weight and mainly composed of α-d-Glucopyranose.•CVPs show high hypoglycemic and hypolipidemic properties in diabetic mice.•CVPs show protective effect on related tissues by pathological histology.•CVPs with high dose are safe for normal mice. It is the first time...

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Veröffentlicht in:	Food and chemical toxicology 2013-07, Vol.57, p.39-45
Hauptverfasser:	Liu, Yuntao, Sun, Jun, Rao, Shengqi, Su, Yujie, Yang, Yanjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Agaricales - chemistry Animals Antioxidants - metabolism Antioxidants - pharmacology Biological and medical sciences Blood Glucose - metabolism Cholesterol - blood Cholesterol, LDL - blood Diabetes mellitus Diabetes Mellitus, Experimental - blood Diabetes Mellitus, Experimental - drug therapy Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Enzymes - metabolism Etiopathogenesis. Screening. Investigations. Target tissue resistance Hypoglycemic Agents - pharmacology Hypolipidemic Agents - pharmacology Kidney - drug effects Kidney - metabolism Kidney - pathology Liver - drug effects Liver - metabolism Liver - pathology Male Medical sciences Mice Mice, Inbred ICR Molecular Weight Mushroom Pancreas - drug effects Pancreas - pathology Polysaccharides Polysaccharides - chemistry Polysaccharides - pharmacology Streptozocin Streptozotocin Toxicology Triglycerides - blood
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