Relative bioavailability of a paediatric granule formulation of the HIV integrase inhibitor dolutegravir in healthy adult subjects

This study evaluated the pharmacokinetics of a granule formulation of dolutegravir developed as an alternative to tablets for use in paediatric populations. A randomized, open-label study in healthy adults was carried out. Subjects received five treatments in a crossover design: a single dose of dol...

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Veröffentlicht in:	Antiviral therapy 2014-01, Vol.19 (3), p.229-233
Hauptverfasser:	PATEL, Parul, SONG, Ivy, BORLAND, Julie, SHUGUANG CHEN, PEPPERCORN, Amanda, WAJIMA, Toshihiro, FUNAKI, Takeshi, FUJITA, Naomi, HUGHES, John, PISCITELLI, Stephen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Area Under Curve Biological and medical sciences Biological Availability Cross-Over Studies Drug Administration Schedule Female Heterocyclic Compounds, 3-Ring - blood Heterocyclic Compounds, 3-Ring - pharmacokinetics HIV Integrase Inhibitors - blood HIV Integrase Inhibitors - pharmacokinetics Human immunodeficiency virus Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments Surveys and Questionnaires Tablets
Online-Zugang:	Volltext
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