Stress and excitatory synapses: From health to disease
Highlights • Stress can result in highly adaptive responses but is also an important risk factor for disease. • Acute stress rapidly enhances excitatory synaptic transmission and promotes learning and memory processes. • Chronic stress reduces excitatory synaptic transmission and learning and memory...
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Veröffentlicht in: | Neuroscience 2013-09, Vol.248, p.626-636 |
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creator | Timmermans, W Xiong, H Hoogenraad, C.C Krugers, H.J |
description | Highlights • Stress can result in highly adaptive responses but is also an important risk factor for disease. • Acute stress rapidly enhances excitatory synaptic transmission and promotes learning and memory processes. • Chronic stress reduces excitatory synaptic transmission and learning and memory. • Early life experience has long-lasting effects on excitatory synaptic transmission and dendritic complexity. |
doi_str_mv | 10.1016/j.neuroscience.2013.05.043 |
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subjects | Adaptation, Physiological Adrenal Cortex Hormones - physiology AMPA Anxiety Disorders - etiology Anxiety Disorders - physiopathology Biological and medical sciences corticosterone Depressive Disorder - etiology Depressive Disorder - physiopathology Fundamental and applied biological sciences. Psychology Humans Life Change Events Neurology Neuronal Plasticity NMDA Norepinephrine - physiology plasticity stress Stress, Psychological - complications Stress, Psychological - physiopathology Stress, Psychological - psychology synapses Synapses - physiology Synaptic Transmission - physiology Vertebrates: nervous system and sense organs |
title | Stress and excitatory synapses: From health to disease |
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