Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors I- and I3 for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection

The peroxisome proliferator-activated receptors (PPARs) belong to the nuclear receptor superfamily. In the last years novel PPARs ligands have been identified and these include PPARI-/I3 dual agonists. To rapidly identify novel PPARs dual ligands, a robust binding assay amenable to high-throughput s...

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Veröffentlicht in:	Journal of Chromatography A 2013-04, Vol.1284, p.36-43
Hauptverfasser:	Temporini, C, Pochetti, G, Fracchiolla, G, Piemontese, L, Montanari, R, Moaddel, R, Laghezza, A, Altieri, F, Cervoni, L, Ubiali, D, Prada, E, Loiodice, F, Massolini, G, Calleri, E
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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