Tunable thick polymer coatings for on-chip electrophoretic protein and peptide separation

► We developed a robust thick wall coating for CE and CEC on chip and capillary. ► Deformation of a monolith resulted in surface coatings with tunable thickness. ► The coating eliminates non-specific protein adsorption and allows control of EOF. ► The coating can be used under acidic and alkaline pH...

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of Chromatography A 2012-06, Vol.1241, p.112-116
Hauptverfasser:	He, Mei, Zeng, Yong, Jemere, Abebaw B., Jed Harrison, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	adsorption Animals Capillary electrophoresis Cattle chromatography coatings durability Electroosmosis Electrophoresis, Microchip - instrumentation Electrophoresis, Microchip - methods Methacrylates - chemistry Microfluidics Open-tubular electrochromatography Peptide Fragments - analysis Peptide Fragments - isolation & purification polymers Polymers - chemistry Serum Albumin, Bovine - chemistry Serum Albumin, Bovine - isolation & purification Thick polymer coating
Online-Zugang:	Volltext
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