Membrane aging during cell growth ascertained by laurdan generalized polarization

The sensitivity of the fluorescent probe Laurdan to the phase state of lipids has been utilized to detect modifications in the composition and physical state of cell membranes during cell growth. In phospholipid vesicles, the Laurdan emission spectrum shows a 50-nm red shift by passing from the gel...

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Veröffentlicht in:	Experimental cell research 1992-10, Vol.202 (2), p.432-439
Hauptverfasser:	Parasassi, Tiziana, Di Stefano, Massimo, Ravagnan, Giampietro, Sapora, Orazio, Gratton, Enrico
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Naphthylamine - analogs & derivatives aging Biological and medical sciences Cell cycle, cell proliferation Cell Division Cell Line Cell Membrane - physiology Cell physiology Cellular Senescence Cholesterol - physiology Fluorescence Polarization Fluorescent Dyes Fundamental and applied biological sciences. Psychology growth K-562 cells Kinetics Laurates man membranes Molecular and cellular biology polarization
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