Polymorphisms in endothelial nitric oxide synthase gene in early and late severe preeclampsia

•NO pathway seems to play a central role in uteroplacental changes during pregnancy.•Preeclampsia (PE) is associated with endothelial dysfunction.•Polymorphism in eNOS gene compromises NO bioavailability.•It has been admitted that early PE and late PE are different diseases.•Contradictory conclusion...

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Veröffentlicht in:	Nitric oxide 2014-11, Vol.42, p.19-23
Hauptverfasser:	Alpoim, Patrícia Nessralla, Gomes, Karina Braga, Pinheiro, Melina de Barros, Godoi, Lara Carvalho, Jardim, Letícia Lemos, Muniz, Ludmila Gomes, Sandrim, Valéria C., Fernandes, Ana Paula, Dusse, Luci Maria S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Case-Control Studies DNA Primers Early/late preeclampsia Endothelial nitric oxide synthase gene Female Humans Nitric oxide Nitric Oxide Synthase Type III - genetics Polymerase Chain Reaction Polymorphism, Genetic Polymorphisms Pregnancy Severity of Illness Index
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