Effect of Intracycle Motion Correction Algorithm on Image Quality and Diagnostic Performance of Computed Tomography Coronary Angiography in Patients with Suspected Coronary Artery Disease
Rationale and objectives We sought to explore the impact of intracycle motion correction algorithms (MCA) in the interpretability and diagnostic accuracy of computed tomography coronary angiography (CTCA) performed in patients suspected of coronary artery disease (CAD) referred to invasive coronary...
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description | Rationale and objectives We sought to explore the impact of intracycle motion correction algorithms (MCA) in the interpretability and diagnostic accuracy of computed tomography coronary angiography (CTCA) performed in patients suspected of coronary artery disease (CAD) referred to invasive coronary angiography. Materials and Methods Patients with suspected CAD referred to invasive coronary angiography previously underwent CTCA. Patients under rate-control medications were advised to withhold for the previous 24 hours. The primary end point of the study was to evaluate image interpretability and diagnostic performance of MCA compared to conventional reconstructions in patients referred to invasive angiography because of suspected CAD. Results Thirty-five patients were prospectively included in the study protocol. The mean age was 61.4 ± 9.4 years. Twenty-seven (77%) patients were men. A total of 533 coronary segments were evaluated using conventional and MCA reconstructions. MCA reconstructions were associated to higher interpretability rates (525 of 533, 98.5% vs. 515 of 533, 96.6 %; P |
doi_str_mv | 10.1016/j.acra.2014.07.016 |
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Materials and Methods Patients with suspected CAD referred to invasive coronary angiography previously underwent CTCA. Patients under rate-control medications were advised to withhold for the previous 24 hours. The primary end point of the study was to evaluate image interpretability and diagnostic performance of MCA compared to conventional reconstructions in patients referred to invasive angiography because of suspected CAD. Results Thirty-five patients were prospectively included in the study protocol. The mean age was 61.4 ± 9.4 years. Twenty-seven (77%) patients were men. A total of 533 coronary segments were evaluated using conventional and MCA reconstructions. MCA reconstructions were associated to higher interpretability rates (525 of 533, 98.5% vs. 515 of 533, 96.6 %; P < .001) and image quality scores (3.88 ± 0.54 vs. 3.78 ± 0.76; P < .0001) compared to conventional reconstructions. Although only mild, a significant difference was observed regarding the diagnostic performance between reconstruction modes, with an area under the curve of 0.90 (0.87–0.92) versus 0.89 (0.86–0.92), respectively, for MCA and conventional reconstructions ( P = .0447). Conclusions In this pilot investigation, MCA reconstructions performed in patients with suspected CAD were associated to higher interpretability rates and image quality scores compared to conventional reconstructions, although only mild differences were observed regarding the diagnostic performance between reconstruction modes.</description><identifier>ISSN: 1076-6332</identifier><identifier>EISSN: 1878-4046</identifier><identifier>DOI: 10.1016/j.acra.2014.07.016</identifier><identifier>PMID: 25281361</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Algorithms ; Cardiac-Gated Imaging Techniques - methods ; Coronary Angiography - methods ; Coronary Artery Disease - diagnostic imaging ; Female ; Humans ; Imaging ; interpretability ; Male ; Middle Aged ; Motion ; multidetector ; Pilot Projects ; Radiographic Image Enhancement - methods ; Radiographic Image Interpretation, Computer-Assisted - methods ; Radiology ; Reproducibility of Results ; Sensitivity and Specificity ; Tomography, X-Ray Computed - methods ; β-blockers</subject><ispartof>Academic radiology, 2015-01, Vol.22 (1), p.81-86</ispartof><rights>AUR</rights><rights>2015 AUR</rights><rights>Copyright © 2015 AUR. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c525t-f740fd967654253ac5e3e8ab41e49f550a08b35dee1c54ed448e30a75643425e3</citedby><cites>FETCH-LOGICAL-c525t-f740fd967654253ac5e3e8ab41e49f550a08b35dee1c54ed448e30a75643425e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.acra.2014.07.016$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25281361$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Carrascosa, Patricia, MD, PhD</creatorcontrib><creatorcontrib>Deviggiano, Alejandro, MD</creatorcontrib><creatorcontrib>Capunay, Carlos, MD</creatorcontrib><creatorcontrib>De Zan, Macarena C., MD</creatorcontrib><creatorcontrib>Goldsmit, Alejandro, MD</creatorcontrib><creatorcontrib>Rodriguez-Granillo, Gaston A., MD, PhD</creatorcontrib><title>Effect of Intracycle Motion Correction Algorithm on Image Quality and Diagnostic Performance of Computed Tomography Coronary Angiography in Patients with Suspected Coronary Artery Disease</title><title>Academic radiology</title><addtitle>Acad Radiol</addtitle><description>Rationale and objectives We sought to explore the impact of intracycle motion correction algorithms (MCA) in the interpretability and diagnostic accuracy of computed tomography coronary angiography (CTCA) performed in patients suspected of coronary artery disease (CAD) referred to invasive coronary angiography. Materials and Methods Patients with suspected CAD referred to invasive coronary angiography previously underwent CTCA. Patients under rate-control medications were advised to withhold for the previous 24 hours. The primary end point of the study was to evaluate image interpretability and diagnostic performance of MCA compared to conventional reconstructions in patients referred to invasive angiography because of suspected CAD. Results Thirty-five patients were prospectively included in the study protocol. The mean age was 61.4 ± 9.4 years. Twenty-seven (77%) patients were men. A total of 533 coronary segments were evaluated using conventional and MCA reconstructions. MCA reconstructions were associated to higher interpretability rates (525 of 533, 98.5% vs. 515 of 533, 96.6 %; P < .001) and image quality scores (3.88 ± 0.54 vs. 3.78 ± 0.76; P < .0001) compared to conventional reconstructions. Although only mild, a significant difference was observed regarding the diagnostic performance between reconstruction modes, with an area under the curve of 0.90 (0.87–0.92) versus 0.89 (0.86–0.92), respectively, for MCA and conventional reconstructions ( P = .0447). Conclusions In this pilot investigation, MCA reconstructions performed in patients with suspected CAD were associated to higher interpretability rates and image quality scores compared to conventional reconstructions, although only mild differences were observed regarding the diagnostic performance between reconstruction modes.</description><subject>Algorithms</subject><subject>Cardiac-Gated Imaging Techniques - methods</subject><subject>Coronary Angiography - methods</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Female</subject><subject>Humans</subject><subject>Imaging</subject><subject>interpretability</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Motion</subject><subject>multidetector</subject><subject>Pilot Projects</subject><subject>Radiographic Image Enhancement - methods</subject><subject>Radiographic Image Interpretation, Computer-Assisted - methods</subject><subject>Radiology</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>β-blockers</subject><issn>1076-6332</issn><issn>1878-4046</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9Uk1v1DAQjRCIfsAf4IB85JLg72QlhLTaFlipiKKWs-V1JlsviR1sB5Tf1j-Ho21B4sBpxuP33tjzpiheEVwRTOTbQ6VN0BXFhFe4rnLpSXFKmropOebyac5xLUvJGD0pzmI8YEyEbNjz4oQK2hAmyWlxf9l1YBLyHdq6FLSZTQ_os0_WO7TxIeTLJV33ex9suhtQPmwHvQf0ddK9TTPSrkUXVu-dj8kadA2h82HQzsCiuvHDOCVo0a0f_D7o8W5edL3TYUZrt7ePRevQtU4WXIroV-6EbqY45u6Z-hcfEuRwYSPoCC-KZ53uI7x8iOfFtw-Xt5tP5dWXj9vN-qo0gopUdjXHXbuStRScCqaNAAaN3nECfNUJgTVudky0AMQIDi3nDTCsayE5ywRg58Wbo-4Y_I8JYlKDjQb6XjvwU1REMl7Tmq5ohtIj1AQfY4BOjcEO-emKYLWYpg5qMU0tpilcq1zKpNcP-tNugPYP5dGlDHh3BED-5U8LQUWTB2WgtYs_qvX2__rv_6Gb3jprdP8dZogHPwWX56eIilRhdbOszbI1hGPMMJbsNyRVwNU</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Carrascosa, Patricia, MD, PhD</creator><creator>Deviggiano, Alejandro, MD</creator><creator>Capunay, Carlos, MD</creator><creator>De Zan, Macarena C., MD</creator><creator>Goldsmit, Alejandro, MD</creator><creator>Rodriguez-Granillo, Gaston A., MD, PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150101</creationdate><title>Effect of Intracycle Motion Correction Algorithm on Image Quality and Diagnostic Performance of Computed Tomography Coronary Angiography in Patients with Suspected Coronary Artery Disease</title><author>Carrascosa, Patricia, MD, PhD ; Deviggiano, Alejandro, MD ; Capunay, Carlos, MD ; De Zan, Macarena C., MD ; Goldsmit, Alejandro, MD ; Rodriguez-Granillo, Gaston A., MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-f740fd967654253ac5e3e8ab41e49f550a08b35dee1c54ed448e30a75643425e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Algorithms</topic><topic>Cardiac-Gated Imaging Techniques - methods</topic><topic>Coronary Angiography - methods</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Female</topic><topic>Humans</topic><topic>Imaging</topic><topic>interpretability</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Motion</topic><topic>multidetector</topic><topic>Pilot Projects</topic><topic>Radiographic Image Enhancement - methods</topic><topic>Radiographic Image Interpretation, Computer-Assisted - methods</topic><topic>Radiology</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>β-blockers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Carrascosa, Patricia, MD, PhD</creatorcontrib><creatorcontrib>Deviggiano, Alejandro, MD</creatorcontrib><creatorcontrib>Capunay, Carlos, MD</creatorcontrib><creatorcontrib>De Zan, Macarena C., MD</creatorcontrib><creatorcontrib>Goldsmit, Alejandro, MD</creatorcontrib><creatorcontrib>Rodriguez-Granillo, Gaston A., MD, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Academic radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Carrascosa, Patricia, MD, PhD</au><au>Deviggiano, Alejandro, MD</au><au>Capunay, Carlos, MD</au><au>De Zan, Macarena C., MD</au><au>Goldsmit, Alejandro, MD</au><au>Rodriguez-Granillo, Gaston A., MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Intracycle Motion Correction Algorithm on Image Quality and Diagnostic Performance of Computed Tomography Coronary Angiography in Patients with Suspected Coronary Artery Disease</atitle><jtitle>Academic radiology</jtitle><addtitle>Acad Radiol</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>22</volume><issue>1</issue><spage>81</spage><epage>86</epage><pages>81-86</pages><issn>1076-6332</issn><eissn>1878-4046</eissn><abstract>Rationale and objectives We sought to explore the impact of intracycle motion correction algorithms (MCA) in the interpretability and diagnostic accuracy of computed tomography coronary angiography (CTCA) performed in patients suspected of coronary artery disease (CAD) referred to invasive coronary angiography. Materials and Methods Patients with suspected CAD referred to invasive coronary angiography previously underwent CTCA. Patients under rate-control medications were advised to withhold for the previous 24 hours. The primary end point of the study was to evaluate image interpretability and diagnostic performance of MCA compared to conventional reconstructions in patients referred to invasive angiography because of suspected CAD. Results Thirty-five patients were prospectively included in the study protocol. The mean age was 61.4 ± 9.4 years. Twenty-seven (77%) patients were men. A total of 533 coronary segments were evaluated using conventional and MCA reconstructions. MCA reconstructions were associated to higher interpretability rates (525 of 533, 98.5% vs. 515 of 533, 96.6 %; P < .001) and image quality scores (3.88 ± 0.54 vs. 3.78 ± 0.76; P < .0001) compared to conventional reconstructions. Although only mild, a significant difference was observed regarding the diagnostic performance between reconstruction modes, with an area under the curve of 0.90 (0.87–0.92) versus 0.89 (0.86–0.92), respectively, for MCA and conventional reconstructions ( P = .0447). Conclusions In this pilot investigation, MCA reconstructions performed in patients with suspected CAD were associated to higher interpretability rates and image quality scores compared to conventional reconstructions, although only mild differences were observed regarding the diagnostic performance between reconstruction modes.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25281361</pmid><doi>10.1016/j.acra.2014.07.016</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Algorithms Cardiac-Gated Imaging Techniques - methods Coronary Angiography - methods Coronary Artery Disease - diagnostic imaging Female Humans Imaging interpretability Male Middle Aged Motion multidetector Pilot Projects Radiographic Image Enhancement - methods Radiographic Image Interpretation, Computer-Assisted - methods Radiology Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed - methods β-blockers |
title | Effect of Intracycle Motion Correction Algorithm on Image Quality and Diagnostic Performance of Computed Tomography Coronary Angiography in Patients with Suspected Coronary Artery Disease |
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