Gastric Mixed Adenoneuroendocrine Carcinoma with a Good Prognosis
A flat, elevated lesion measuring 5 mm in diameter was found in the gastric body of an 80-year-old man. A biopsy showed moderately differentiated adenocarcinoma, and endoscopic ultrasonography revealed a hypoechoic mass located in the submucosa. Endoscopic submucosal dissection was subsequently perf...
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| Veröffentlicht in: | Internal Medicine 2014, Vol.53(22), pp.2585-2588 |
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| container_title | Internal Medicine |
| container_volume | 53 |
| creator | Fukuba, Nobuhiko Yuki, Takafumi Ishihara, Shunji Sonoyama, Hiroki Tada, Yasumasa Kusunoki, Ryusaku Oka, Akihiko Oshima, Naoki Moriyama, Ichiro Kawashima, Kousaku Kinoshita, Yoshikazu |
| description | A flat, elevated lesion measuring 5 mm in diameter was found in the gastric body of an 80-year-old man. A biopsy showed moderately differentiated adenocarcinoma, and endoscopic ultrasonography revealed a hypoechoic mass located in the submucosa. Endoscopic submucosal dissection was subsequently performed, and a pathological examination revealed a tumor composed of adenocarcinoma and neuroendocrine carcinoma with submucosal infiltration. The pathological diagnosis was gastric mixed adenoneuroendocrine carcinoma (MANEC). An additional gastrectomy procedure was performed, and no recurrence was noted for at least three years. This case is interesting with respect to the carcinogenesis of endocrine cell carcinoma and MANEC. |
| doi_str_mv | 10.2169/internalmedicine.53.3328 |
| format | Article |
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A biopsy showed moderately differentiated adenocarcinoma, and endoscopic ultrasonography revealed a hypoechoic mass located in the submucosa. Endoscopic submucosal dissection was subsequently performed, and a pathological examination revealed a tumor composed of adenocarcinoma and neuroendocrine carcinoma with submucosal infiltration. The pathological diagnosis was gastric mixed adenoneuroendocrine carcinoma (MANEC). An additional gastrectomy procedure was performed, and no recurrence was noted for at least three years. 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Med.</addtitle><description>A flat, elevated lesion measuring 5 mm in diameter was found in the gastric body of an 80-year-old man. A biopsy showed moderately differentiated adenocarcinoma, and endoscopic ultrasonography revealed a hypoechoic mass located in the submucosa. Endoscopic submucosal dissection was subsequently performed, and a pathological examination revealed a tumor composed of adenocarcinoma and neuroendocrine carcinoma with submucosal infiltration. The pathological diagnosis was gastric mixed adenoneuroendocrine carcinoma (MANEC). An additional gastrectomy procedure was performed, and no recurrence was noted for at least three years. This case is interesting with respect to the carcinogenesis of endocrine cell carcinoma and MANEC.</description><subject>Aged, 80 and over</subject><subject>Biopsy</subject><subject>Carcinoma, Neuroendocrine - diagnosis</subject><subject>Carcinoma, Neuroendocrine - surgery</subject><subject>Endosonography</subject><subject>Gastrectomy</subject><subject>gastric cancer</subject><subject>good prognosis</subject><subject>Humans</subject><subject>Male</subject><subject>mixed adenoneuroendocrine carcinoma</subject><subject>Prognosis</subject><subject>Stomach Neoplasms - diagnosis</subject><subject>Stomach Neoplasms - surgery</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkL1uGzEQhAkjRiTLeQXjyjQn8_fIKwUhUQw4UAq7Jnjk0qZwIh3yhCRvHwqSVQQpdrbYb2eAQagheElJ19-HOEGOZtyDCzZEWAq2ZIyqKzQnjPetpEx8QHPcE9XSKjN0U8oOY6ZkTz-iGRUcYyL7OVptTJlysM338Btcs3IQU4RDThBdsrl6N2uTa0bam-ZXmF4b02xScs2PnF5iKqHcomtvxgKfznuBnr9-eVp_ax-3m4f16rG1gsqpdQwGhztg0vRcCImlJa6nvPOWC8Wt84PnrI5SlffUk0F10qvBE-iwZ2yBPp9833L6eYAy6X0oFsbRREiHoknHOO8lE7yi6oTanErJ4PVbDnuT_2iC9bFA_W-BWjB9LLC-3p1TDkM9Xh7fG6vA9gTsymRe4AKYPAU7wn-dKT3qOeJC2leTNUT2F1tzjv0</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Fukuba, Nobuhiko</creator><creator>Yuki, Takafumi</creator><creator>Ishihara, Shunji</creator><creator>Sonoyama, Hiroki</creator><creator>Tada, Yasumasa</creator><creator>Kusunoki, Ryusaku</creator><creator>Oka, Akihiko</creator><creator>Oshima, Naoki</creator><creator>Moriyama, Ichiro</creator><creator>Kawashima, Kousaku</creator><creator>Kinoshita, Yoshikazu</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140101</creationdate><title>Gastric Mixed Adenoneuroendocrine Carcinoma with a Good Prognosis</title><author>Fukuba, Nobuhiko ; Yuki, Takafumi ; Ishihara, Shunji ; Sonoyama, Hiroki ; Tada, Yasumasa ; Kusunoki, Ryusaku ; Oka, Akihiko ; Oshima, Naoki ; Moriyama, Ichiro ; Kawashima, Kousaku ; Kinoshita, Yoshikazu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c527t-d3ebd06e37a9455707c1d9246fc4584cdfbf43bf488527f2f1b867f8bf1e60f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged, 80 and over</topic><topic>Biopsy</topic><topic>Carcinoma, Neuroendocrine - diagnosis</topic><topic>Carcinoma, Neuroendocrine - surgery</topic><topic>Endosonography</topic><topic>Gastrectomy</topic><topic>gastric cancer</topic><topic>good prognosis</topic><topic>Humans</topic><topic>Male</topic><topic>mixed adenoneuroendocrine carcinoma</topic><topic>Prognosis</topic><topic>Stomach Neoplasms - diagnosis</topic><topic>Stomach Neoplasms - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fukuba, Nobuhiko</creatorcontrib><creatorcontrib>Yuki, Takafumi</creatorcontrib><creatorcontrib>Ishihara, Shunji</creatorcontrib><creatorcontrib>Sonoyama, Hiroki</creatorcontrib><creatorcontrib>Tada, Yasumasa</creatorcontrib><creatorcontrib>Kusunoki, Ryusaku</creatorcontrib><creatorcontrib>Oka, Akihiko</creatorcontrib><creatorcontrib>Oshima, Naoki</creatorcontrib><creatorcontrib>Moriyama, Ichiro</creatorcontrib><creatorcontrib>Kawashima, Kousaku</creatorcontrib><creatorcontrib>Kinoshita, Yoshikazu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fukuba, Nobuhiko</au><au>Yuki, Takafumi</au><au>Ishihara, Shunji</au><au>Sonoyama, Hiroki</au><au>Tada, Yasumasa</au><au>Kusunoki, Ryusaku</au><au>Oka, Akihiko</au><au>Oshima, Naoki</au><au>Moriyama, Ichiro</au><au>Kawashima, Kousaku</au><au>Kinoshita, Yoshikazu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gastric Mixed Adenoneuroendocrine Carcinoma with a Good Prognosis</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>53</volume><issue>22</issue><spage>2585</spage><epage>2588</epage><pages>2585-2588</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>A flat, elevated lesion measuring 5 mm in diameter was found in the gastric body of an 80-year-old man. A biopsy showed moderately differentiated adenocarcinoma, and endoscopic ultrasonography revealed a hypoechoic mass located in the submucosa. Endoscopic submucosal dissection was subsequently performed, and a pathological examination revealed a tumor composed of adenocarcinoma and neuroendocrine carcinoma with submucosal infiltration. The pathological diagnosis was gastric mixed adenoneuroendocrine carcinoma (MANEC). An additional gastrectomy procedure was performed, and no recurrence was noted for at least three years. This case is interesting with respect to the carcinogenesis of endocrine cell carcinoma and MANEC.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>25400179</pmid><doi>10.2169/internalmedicine.53.3328</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Internal Medicine, 2014, Vol.53(22), pp.2585-2588 |
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| subjects | Aged, 80 and over Biopsy Carcinoma, Neuroendocrine - diagnosis Carcinoma, Neuroendocrine - surgery Endosonography Gastrectomy gastric cancer good prognosis Humans Male mixed adenoneuroendocrine carcinoma Prognosis Stomach Neoplasms - diagnosis Stomach Neoplasms - surgery |
| title | Gastric Mixed Adenoneuroendocrine Carcinoma with a Good Prognosis |
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