Consumption of PCB-contaminated Freshwater Fish and Shortened Menstrual Cycle Length
Highly contaminated Lake Ontario sport fish represent an important human dietary exposure to polychlorinated biphenyls (PCBs) and other toxic contaminants that may disrupt endocrine pathways. New York State Angler Cohort women interviewed by telephone in 1993 provided menstrual cycle length (n 2,223...
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Veröffentlicht in: | American journal of epidemiology 1997-12, Vol.146 (11), p.955-960 |
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container_title | American journal of epidemiology |
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creator | Mendola, Pauline Buck, Germaine M. Sever, Lowell E. Zielezny, Maria Vena, John E. |
description | Highly contaminated Lake Ontario sport fish represent an important human dietary exposure to polychlorinated biphenyls (PCBs) and other toxic contaminants that may disrupt endocrine pathways. New York State Angler Cohort women interviewed by telephone in 1993 provided menstrual cycle length (n 2,223). Fish consumption at cohort enrollment in 1991 was categorized by duration and frequency and was used to calculate a PCB exposure index. Multiple regression analyses identified significant cycle length reductions with consumption of more than one fish meal per month (1.11 days) and moderatelhigh estimated PCB index (−1.03 days). Women who consumed contaminated fish for 7 years or more also had shorter cycles (−0.63 days). |
doi_str_mv | 10.1093/oxfordjournals.aje.a009222 |
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New York State Angler Cohort women interviewed by telephone in 1993 provided menstrual cycle length (n 2,223). Fish consumption at cohort enrollment in 1991 was categorized by duration and frequency and was used to calculate a PCB exposure index. Multiple regression analyses identified significant cycle length reductions with consumption of more than one fish meal per month (1.11 days) and moderatelhigh estimated PCB index (−1.03 days). 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New York State Angler Cohort women interviewed by telephone in 1993 provided menstrual cycle length (n 2,223). Fish consumption at cohort enrollment in 1991 was categorized by duration and frequency and was used to calculate a PCB exposure index. Multiple regression analyses identified significant cycle length reductions with consumption of more than one fish meal per month (1.11 days) and moderatelhigh estimated PCB index (−1.03 days). Women who consumed contaminated fish for 7 years or more also had shorter cycles (−0.63 days).</description><subject>Adolescent</subject><subject>Adult</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Cohort Studies</subject><subject>Diet</subject><subject>environmental pollutants</subject><subject>Feeding Behavior</subject><subject>Female</subject><subject>Fishes</subject><subject>Food Contamination</subject><subject>Food toxicology</subject><subject>Freshwater</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Menstrual Cycle - drug effects</subject><subject>menstruation</subject><subject>New York</subject><subject>polychlorinated biphenyls</subject><subject>Polychlorinated Biphenyls - adverse effects</subject><subject>Regression Analysis</subject><subject>Toxicology</subject><subject>women</subject><issn>0002-9262</issn><issn>1476-6226</issn><issn>1476-6256</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkF1v0zAUhi3ENMrgJyBFCHGX4m_X3LGIUkSngTY0xI3lOCc0JbGL7Yjt3xPUqNKuzpHe53zoQeg1wUuCNXsX7tsQm30Yo7d9Wto9LC3GmlL6BC0IV7KUlMqnaIExpqWmkj5Dz1PaY0yIFvgcnWuOMWNqgW6r4NM4HHIXfBHa4mt1Wbrgsx06bzM0xTpC2v2d2lisu7QrrG-Km12IGfyUXoFPOY62L6oH10OxBf8r716gs3Z6DF7O9QJ9X3-8rTbl9vrT5-rDtnSC4Vy6lrm6FuCAKVmrFeeKraQSVMmGKQJAV9RxZ_lKiUYyUXPaUqG0FYporgm7QG-Pew8x_BkhZTN0yUHfWw9hTIZIxpnEdALfH0EXQ0oRWnOI3WDjgyHY_FdqHis1k1IzK52GX81XxnqA5jQ6O5zyN3Nuk7N9G613XTphFCuuhZ6w8oh1KcP9Kbbxt5GKKWE2P36amy9Mb77d3RnF_gGkbZRM</recordid><startdate>19971201</startdate><enddate>19971201</enddate><creator>Mendola, Pauline</creator><creator>Buck, Germaine M.</creator><creator>Sever, Lowell E.</creator><creator>Zielezny, Maria</creator><creator>Vena, John E.</creator><general>Oxford University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7TV</scope><scope>7U1</scope><scope>7U2</scope><scope>7U7</scope><scope>C1K</scope><scope>F1W</scope><scope>H97</scope><scope>L.G</scope></search><sort><creationdate>19971201</creationdate><title>Consumption of PCB-contaminated Freshwater Fish and Shortened Menstrual Cycle Length</title><author>Mendola, Pauline ; Buck, Germaine M. ; Sever, Lowell E. ; Zielezny, Maria ; Vena, John E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c530t-cf3cbb5ece376b7844738675276d371ee282c4ca4875d635b42f2579a57194913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Cohort Studies</topic><topic>Diet</topic><topic>environmental pollutants</topic><topic>Feeding Behavior</topic><topic>Female</topic><topic>Fishes</topic><topic>Food Contamination</topic><topic>Food toxicology</topic><topic>Freshwater</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Menstrual Cycle - drug effects</topic><topic>menstruation</topic><topic>New York</topic><topic>polychlorinated biphenyls</topic><topic>Polychlorinated Biphenyls - adverse effects</topic><topic>Regression Analysis</topic><topic>Toxicology</topic><topic>women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mendola, Pauline</creatorcontrib><creatorcontrib>Buck, Germaine M.</creatorcontrib><creatorcontrib>Sever, Lowell E.</creatorcontrib><creatorcontrib>Zielezny, Maria</creatorcontrib><creatorcontrib>Vena, John E.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Pollution Abstracts</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>American journal of epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mendola, Pauline</au><au>Buck, Germaine M.</au><au>Sever, Lowell E.</au><au>Zielezny, Maria</au><au>Vena, John E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Consumption of PCB-contaminated Freshwater Fish and Shortened Menstrual Cycle Length</atitle><jtitle>American journal of epidemiology</jtitle><addtitle>Am J Epidemiol</addtitle><date>1997-12-01</date><risdate>1997</risdate><volume>146</volume><issue>11</issue><spage>955</spage><epage>960</epage><pages>955-960</pages><issn>0002-9262</issn><eissn>1476-6226</eissn><eissn>1476-6256</eissn><coden>AJEPAS</coden><abstract>Highly contaminated Lake Ontario sport fish represent an important human dietary exposure to polychlorinated biphenyls (PCBs) and other toxic contaminants that may disrupt endocrine pathways. New York State Angler Cohort women interviewed by telephone in 1993 provided menstrual cycle length (n 2,223). Fish consumption at cohort enrollment in 1991 was categorized by duration and frequency and was used to calculate a PCB exposure index. Multiple regression analyses identified significant cycle length reductions with consumption of more than one fish meal per month (1.11 days) and moderatelhigh estimated PCB index (−1.03 days). Women who consumed contaminated fish for 7 years or more also had shorter cycles (−0.63 days).</abstract><cop>Cary, NC</cop><pub>Oxford University Press</pub><pmid>9400337</pmid><doi>10.1093/oxfordjournals.aje.a009222</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Adolescent Adult Animals Biological and medical sciences Cohort Studies Diet environmental pollutants Feeding Behavior Female Fishes Food Contamination Food toxicology Freshwater Humans Medical sciences Menstrual Cycle - drug effects menstruation New York polychlorinated biphenyls Polychlorinated Biphenyls - adverse effects Regression Analysis Toxicology women |
title | Consumption of PCB-contaminated Freshwater Fish and Shortened Menstrual Cycle Length |
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