Synthesis and biological evaluation of new BSH-conjugated chlorin derivatives as agents for both photodynamic therapy and boron neutron capture therapy of cancer
•Four new BSH-conjugated chlorin derivatives for both PDT and BNCT were synthesized.•The in vivo biodistribution and clearance of the four derivatives were investigated.•Two derivatives showed good tumor-selective accumulation.•Tumor growth was significantly inhibited by PDT using one of the derivat...
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Veröffentlicht in: | Journal of photochemistry and photobiology. B, Biology Biology, 2014-11, Vol.140, p.140-149 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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