Bone Marrow Stromal Cells Combined with Oxiracetam Influences the Expression of B-cell Lymphoma 2 in Rats with Ischemic Stroke

This study aimed to investigate the combination effects of bone marrow stromal cells (BMSCs) and oxiracetam for ischemic stroke. Forty Sprague Dawley female rats (220 ± 20 g) were subjected to a 2-hour ischemic middle cerebral artery occlusion (MCAO)–24 hours reperfusion model. The rats were randoml...

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Veröffentlicht in:	Journal of stroke and cerebrovascular diseases 2014-11, Vol.23 (10), p.2591-2597
Hauptverfasser:	Wang, Chunyan, MM, Li, Fangqin, MM, Guan, Yu, MM, Zhu, Lei, MM, Fei, Yiping, MD, Zhang, Jiadong, MM, Pan, Yujun, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bcl-2 BMSCs Bone Marrow Cells - cytology Bone Marrow Cells - metabolism Bone Marrow Transplantation - methods Brain Ischemia - metabolism Brain Ischemia - therapy Cardiovascular Combined Modality Therapy - methods Disease Models, Animal Dose-Response Relationship, Drug Female Ischemic stroke Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - metabolism Neurology Nootropic Agents - pharmacology oxiracetam Proto-Oncogene Proteins c-bcl-2 - metabolism Pyrrolidines - administration & dosage Pyrrolidines - pharmacology Rats Rats, Sprague-Dawley Stroke - metabolism Stroke - therapy Treatment Outcome Up-Regulation - drug effects
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