Differential effects of methylmercury, thiols, and vitamins on galactosidases of nervous and non-nervous tissues

Mice were given daily doses of methylmercuric chloride at a dose rate of 1mg/kg body weight for one week. Some animals were then treated for one week with one of the antagonists, N-acetyl-DL-homocysteine thiolactone or glutathione (GSH). Other groups received vitamin therapy for one week. The vitami...

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Veröffentlicht in:	Bulletin of Environmental Contamination and Toxicology 1992-07, Vol.49 (1), p.71-77
Hauptverfasser:	VIJAYALAKSHMI, K, BAPU, C, SOOD, P. P
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Galactosidase - drug effects Animals beta-Galactosidase - drug effects BIOCHEMISTRY Biological and medical sciences BIOLOGICAL EFFECTS BIOLOGICAL PATHWAYS BIOLOGY AND MEDICINE, APPLIED STUDIES BIOLOGY AND MEDICINE, BASIC STUDIES Brain - drug effects Brain - enzymology Chemical and industrial products toxicology. Toxic occupational diseases DETOXIFICATION GALACTOSIDASE Glutathione - pharmacology Kidney - drug effects Kidney - enzymology Lysosomes - enzymology Male Medical sciences Metals and various inorganic compounds METHYLMERCURY Methylmercury Compounds - toxicity MICE Mice, Inbred Strains Nerve Tissue - drug effects Nerve Tissue - enzymology Spinal Cord - drug effects Spinal Cord - enzymology Sulfhydryl Compounds - pharmacology Testis - drug effects Testis - enzymology THERAPEUTIC USES THIOLS Thiophenes - pharmacology Toxicology VITAMINS Vitamins - pharmacology
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