Reconstitution of alpha sub(1)-adrenoceptors having high affinity for prazosin

Using a variety of detergents we find that soluble alpha sub(1)-adrenoceptor recovery from aortic and hepatic membranes is markedly enhanced if the receptor is first prelabelled with prazosin. Moreover, prelabelling prevents the reduction in prazosin affinity induced by solubilizing concentrations o...

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Veröffentlicht in:	European journal of pharmacology 1992-01, Vol.226 (3), p.191-197
Hauptverfasser:	Valliere, JE, DeLuca, A W, Shreeve, S M
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha -adrenergic prazosin receptors reconstitution
Online-Zugang:	Volltext
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