A comparative trial of zidovudine administered every four versus every twelve hours for the treatment of advanced HIV disease

Zidovudine is approved for administration in doses given every 4 hours. Less frequent dosing has been used in many clinical trials, but the toxicity and efficacy of such regimens have not been formally compared with the approved regimen. In this multicenter, randomized, double-blind, controlled tria...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes and human retrovirology 1997-08, Vol.15 (4), p.283-288
Hauptverfasser:	SHEPP, D. H, RAMIREZ-RONDA, T, GREENBERG, S. B, PETERSEN, E, FRANK, I, MOORE, M. D, MCKINNIS, R, ROONEY, J. F, DALL, L, POLLARD, R. B, MURPHY, R. L, KESSLER, H, SHERER, R, MERTZ, G, PEREZ, G, GOCKE, D. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Drug Administration Schedule Female HIV Infections - drug therapy Humans Male Medical sciences Pharmacology. Drug treatments Zidovudine - administration & dosage Zidovudine - adverse effects
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