Toxicity assessment of toxins T-514 and T-544 of buckthorn ( Karwinskia humboldtiana) in primary skin and liver cell cultures

The present study was undertaken to assess and compare the in vitro cytotoxicity of toxins T-514 and T-544 of buckthorn ( Karwinskia humboldtiana) using primary cultures of rat hepatocytes and keratinocytes. Cell cultures were exposed to 6, 12, 25 and 50 μM toxins for 2-, 4-, 6- and 24-h peroids. Cy...

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