Preparation and characterization of magnetic gold nanoparticles to be used as doxorubicin nanocarriers

Abstract Magnetic targeted drug delivery (MTD), using magnetic gold nanoparticles (Fe3 O4 @Au NPs) conjugated with an anti-cancer drug is a promise modality for cancer treatment. In this study, Fe3 O4 @Au NPs were prepared and functionalized with thiol-terminated polyethylene glycol (PEG), then load...

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Veröffentlicht in:	Physica medica 2014-11, Vol.30 (7), p.843-848
Hauptverfasser:	Elbialy, Nihal Saad, Fathy, Mohammed Mahmoud, Khalil, Wafaa Mohamed
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Doxorubicin Doxorubicin - chemistry Doxorubicin - pharmacology Drug Carriers - chemistry Drug delivery Drug Liberation Drug Stability Gold - chemistry Humans Iron oxide nanoparticles Magnetite Nanoparticles - chemistry MCF-7 Cells Nanoparticles Polyethylene Glycols - chemistry Radiology Sulfhydryl Compounds - chemistry Surface Properties
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