Involvement of glucagon-like peptide 1 in the glucose homeostasis regulation in obese and pituitary-dependent hyperadrenocorticism affected dogs

•GLP-1 and insulin are increased in PDH affected dogs.•Insulin resistance is more serious in PDH affected dogs than obese dogs.•Dogs affected with PDH fail to control insulin resistance.•HOMA indices are more altered in dogs with PDH. The incretin glucagon-like peptide 1 (GLP-1) enhances insulin sec...

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Veröffentlicht in:	Research in veterinary science 2014-10, Vol.97 (2), p.211-217
Hauptverfasser:	Miceli, D.D., Cabrera Blatter, M.F., Gallelli, M.F., Pignataro, O.P., Castillo, V.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenocortical Hyperfunction - metabolism Adrenocortical Hyperfunction - physiopathology Adrenocortical Hyperfunction - veterinary Animals Blood Glucose - metabolism Diabetes Mellitus - epidemiology Diabetes Mellitus - metabolism Dog Diseases - metabolism Dog Diseases - physiopathology Dogs - physiology Female Glucagon-Like Peptide 1 - blood Glucagon-Like Peptide 1 - physiology Glucagon-like-peptide-1 Glucose Glucose - metabolism Glucose Tolerance Test - veterinary Homeostasis - physiology Insulin Insulin - blood Insulin resistance Male Obesity - metabolism Obesity - physiopathology Obesity - veterinary Oral glucose tolerance test Pancreas Pituitary ACTH Hypersecretion - metabolism Pituitary ACTH Hypersecretion - physiopathology Pituitary ACTH Hypersecretion - veterinary Pituitary-dependent hyperadrenocorticism Risk Factors Rodents Secondary diabetes Time Factors Veterinary medicine
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