Giant Left Ventricular Thrombus Formation Associated With Heparin-Induced Thrombocytopenia
A 33-year-old man underwent urgent coronary artery de-obstruction for acute thrombotic occlusion of the left descending coronary artery. After 10 days of antiplatelet and heparin therapy, ventriculographic and echocardiographic control revealed a giant thrombus in the left ventricle, an ejection fra...
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| Veröffentlicht in: | The Annals of thoracic surgery 2014-12, Vol.98 (6), p.e143-e145 |
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| container_title | The Annals of thoracic surgery |
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| creator | Campisi, Salvatore, MD Fuzellier, Jean-Francois, MD Vola, Marco, MD Favre, Jean-Pierre, MD |
| description | A 33-year-old man underwent urgent coronary artery de-obstruction for acute thrombotic occlusion of the left descending coronary artery. After 10 days of antiplatelet and heparin therapy, ventriculographic and echocardiographic control revealed a giant thrombus in the left ventricle, an ejection fraction of 40%, and severe mitral regurgitation. Heparin-induced thrombocytopenia was diagnosed. After urgent mitral valve annuloplasty and left ventricular thrombectomy, the patient was discharged. In the literature, several cases of right atrial and ventricular thrombi have been described; however, to the best of our knowledge, this is the first report of giant left ventricular thrombus during heparin-induced thrombocytopenia. |
| doi_str_mv | 10.1016/j.athoracsur.2014.08.054 |
| format | Article |
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After 10 days of antiplatelet and heparin therapy, ventriculographic and echocardiographic control revealed a giant thrombus in the left ventricle, an ejection fraction of 40%, and severe mitral regurgitation. Heparin-induced thrombocytopenia was diagnosed. After urgent mitral valve annuloplasty and left ventricular thrombectomy, the patient was discharged. In the literature, several cases of right atrial and ventricular thrombi have been described; however, to the best of our knowledge, this is the first report of giant left ventricular thrombus during heparin-induced thrombocytopenia.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2014.08.054</identifier><identifier>PMID: 25468127</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Adult ; Anticoagulants - adverse effects ; Cardiothoracic Surgery ; Echocardiography ; Follow-Up Studies ; Gated Blood-Pool Imaging ; Heart Diseases - diagnosis ; Heart Diseases - etiology ; Heart Diseases - surgery ; Heart Ventricles ; Heparin - adverse effects ; Humans ; Male ; Surgery ; Thrombectomy - methods ; Thrombocytopenia - chemically induced ; Thrombocytopenia - complications ; Thrombosis - diagnosis ; Thrombosis - etiology ; Thrombosis - surgery</subject><ispartof>The Annals of thoracic surgery, 2014-12, Vol.98 (6), p.e143-e145</ispartof><rights>The Society of Thoracic Surgeons</rights><rights>2014 The Society of Thoracic Surgeons</rights><rights>Copyright © 2014 The Society of Thoracic Surgeons. 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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Anticoagulants - adverse effects Cardiothoracic Surgery Echocardiography Follow-Up Studies Gated Blood-Pool Imaging Heart Diseases - diagnosis Heart Diseases - etiology Heart Diseases - surgery Heart Ventricles Heparin - adverse effects Humans Male Surgery Thrombectomy - methods Thrombocytopenia - chemically induced Thrombocytopenia - complications Thrombosis - diagnosis Thrombosis - etiology Thrombosis - surgery |
| title | Giant Left Ventricular Thrombus Formation Associated With Heparin-Induced Thrombocytopenia |
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