Effects of the calcium channel blockers Phα1β and ω-conotoxin MVIIA on capsaicin and acetic acid-induced visceral nociception in mice

The effects of intrathecal administration of the toxins Phα1β and ω-conotoxin MVIIA were investigated in visceral nociception induced by an intraperitoneal injection of acetic acid and an intracolonic application of capsaicin. The pretreatments for 2h with the toxins reduced the number of writhes or...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2014-11, Vol.126, p.97-102
Hauptverfasser:	Diniz, Danuza Montijo, de Souza, Alessandra Hubner, Pereira, Elizete Maria Rita, da Silva, Juliana Figueira, Rigo, Flavia Karine, Romano‐Silva, Marco Aurélio, Binda, Nancy, Castro, Célio J., Cordeiro, Marta Nascimento, Ferreira, Juliano, Gomez, Marcus Vinicius
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid - administration & dosage Acetic Acid - pharmacology Administration, Rectal Animals Calcium channel blockers Calcium Channel Blockers - pharmacology Capsaicin - administration & dosage Capsaicin - pharmacology Dose-Response Relationship, Drug Glutamate Glutamic Acid - cerebrospinal fluid Injections, Spinal Male Mice Nociception - drug effects omega-Conotoxins - pharmacology Reactive Oxygen Species - cerebrospinal fluid ROS Spider Venoms - pharmacology Toxins Visceral nociception
Online-Zugang:	Volltext
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