Patterns of Initiation of Oral Anticoagulants in Patients with Atrial Fibrillation— Quality and Cost Implications

Abstract Background Dabigatran, rivaroxaban, and apixaban have been approved for use in patients with atrial fibrillation based upon randomized trials demonstrating their comparable or superior efficacy and safety relative to warfarin. Little is known about their adoption into clinical practice, whe...

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Veröffentlicht in:	The American journal of medicine 2014-11, Vol.127 (11), p.1075-1082.e1
Hauptverfasser:	Desai, Nihar R., MD, MPH, Krumme, Alexis A., MS, Schneeweiss, Sebastian, MD, ScD, Shrank, William H., MD, MSHS, Brill, Gregory, MS, Pezalla, Edmund J., MD, MPH, Spettell, Claire M., PhD, Brennan, Troyen A., MD, JD, MPH, Matlin, Olga S., PhD, Avorn, Jerry, MD, Choudhry, Niteesh K., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Aged Anticoagulants Anticoagulants - economics Anticoagulants - therapeutic use Atrial Fibrillation - drug therapy Benzimidazoles - economics Benzimidazoles - therapeutic use beta-Alanine - analogs & derivatives beta-Alanine - economics beta-Alanine - therapeutic use Cardiac arrhythmia Clinical trials Dabigatran Databases, Factual Drug Utilization Review Factor Xa inhibitor Factor Xa Inhibitors - economics Factor Xa Inhibitors - therapeutic use Fees, Pharmaceutical Female Health care expenditures Humans Income Internal Medicine Male Middle Aged Morpholines - economics Morpholines - therapeutic use Multivariate Analysis Novel anticoagulant Patterns of use Pyrazoles - economics Pyrazoles - therapeutic use Pyridones - economics Pyridones - therapeutic use Risk Assessment Rivaroxaban Severity of Illness Index Sex Factors Stroke - prevention & control Thiophenes - economics Thiophenes - therapeutic use United States - epidemiology Vitamin K - antagonists & inhibitors Vitamin K antagonist Warfarin Warfarin - economics Warfarin - therapeutic use Young Adult
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