Cytochrome P450-7B1 and 11β-hydroxysteroid dehydrogenase type 1 distribution in human tissues

Successive action of cytochrome P450-7B1 (CYP7B1) and 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) on 3β-hydroxysteroids such as DHEA and epiandrosterone leads to the production of cytoprotective 7β-hydroxylated derivatives. Investigation of the presence of these enzymes in human tissues could...

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Veröffentlicht in:	Hormone molecular biology and clinical investigation 2012-04, Vol.9 (3), p.179-189
Hauptverfasser:	Chalbot, Sonia, Morfin, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	11β-HSD1 brain cervix colon CYP7B1 esophagus liver pancreas parathyroid skin small intestine spleen stomach thyroid uterus
Online-Zugang:	Volltext
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