Study of the protective mechanisms of Compound Danshen Tablet (Fufang Danshen Pian) against myocardial ischemia/reperfusion injury via the Akt-eNOS signaling pathway in rats

Compound Danshen Tablet (CDT), an herbal preparation consisting of Salvia miltiorrhiza (Radix and rhizome of Salvia miltiorrhiza Bge.), Notoginseng (Radix and rhizome of Panax notoginseng (Burk.) F. H. Chen) and Borneolum Syntheticum, is widely used to improve coronary heart disease, cardiac angina...

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Veröffentlicht in:	Journal of ethnopharmacology 2014-10, Vol.156, p.190-198
Hauptverfasser:	Ren-an, Qin, Juan, Lin, Chuyuan, Li, Wenjuan, Fu, Chunyan, Huang, Xuemei, Yu, Lin, Huang, Hong, Nie
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt Animals Apoptosis - drug effects Caspase 3 - metabolism Compound Danshen Tablet Drugs, Chinese Herbal - pharmacology eNOS Heart - drug effects Male Myocardial ischemia/reperfusion injury Myocardial Reperfusion Injury - drug therapy Myocardial Reperfusion Injury - metabolism Myocytes, Cardiac - drug effects Myocytes, Cardiac - metabolism Nitric Oxide Synthase Type III - metabolism Panax notoginseng - chemistry Protective Agents - pharmacology Protective Mechanisms Proto-Oncogene Proteins c-akt - metabolism Proto-Oncogene Proteins c-bcl-2 - metabolism Rats Rats, Sprague-Dawley Salvia miltiorrhiza - chemistry Signal Transduction - drug effects Signaling pathway Tablets - pharmacology
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