Co-existence of Lichen Sclerosus and Localized Scleroderma in Female Monozygotic Twins
Abstract Background Etiology of lichen sclerosus (LiS) and localized scleroderma (LoS) is uncertain and probably multifactorial. Case We describe a case of female monozygotic twins who presented co-existence of LiS and LoS. Skin lesions typical for LoS occurred in both patients, at the age of 10. On...
Gespeichert in:
| Veröffentlicht in: | Journal of pediatric & adolescent gynecology 2014-12, Vol.27 (6), p.e133-e136 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e136 |
|---|---|
| container_issue | 6 |
| container_start_page | e133 |
| container_title | Journal of pediatric & adolescent gynecology |
| container_volume | 27 |
| creator | Lis-Święty, Anna, MD, PhD Mierzwińska, Katarzyna, MD Wodok-Wieczorek, Karolina, MD Widuchowska, Małgorzata, MD, PhD Brzezińska-Wcisło, Ligia, MD, PhD |
| description | Abstract Background Etiology of lichen sclerosus (LiS) and localized scleroderma (LoS) is uncertain and probably multifactorial. Case We describe a case of female monozygotic twins who presented co-existence of LiS and LoS. Skin lesions typical for LoS occurred in both patients, at the age of 10. One sister was diagnosed with linear LoS of the lower limb affecting deeper situated subcutaneous tissue and muscles. The other sister was diagnosed with guttate LoS of the trunk, with slow progression of the skin lesions. In both sisters vulvar LiS developed at the age of 19. Conclusions Co-existence of LiS and LoS in monozygotic twins indicates the possible genetic contribution to the pathogenesis of these diseases and the close relationship between them. |
| doi_str_mv | 10.1016/j.jpag.2013.11.010 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1629970754</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1083318813003446</els_id><sourcerecordid>1629970754</sourcerecordid><originalsourceid>FETCH-LOGICAL-c326t-7488ab869d62ee3607580b8f26f2a56f835c1e51e272dbb0f79eab5e99c8d3b33</originalsourceid><addsrcrecordid>eNp9kUFv1DAQhS0EoqXwBzggH7kkeOzEcSSEhFaUVtqKQwtXy3EmxSGxlzgpbH89jnbbQw-cZjR672nmG0LeAsuBgfzQ5_3O3OacgcgBcgbsGTkFVYmsEII_Tz1TIhOg1Al5FWPPGKtKqV6SE16oAkqoT8mPTcjwr4szeos0dHTr7E_09NoOOIW4RGp8S7fBmsHdY3uctziNhjpPz3E0A9Kr4MP9_jbMztKbP87H1-RFZ4aIb471jHw__3Kzuci2375ebj5vMyu4nLOqUMo0Stat5IhCpv0Ua1THZcdNKTslSgtYAvKKt03DuqpG05RY11a1ohHijLw_5O6m8HvBOOvRRYvDYDyGJWqQvK6rFFskKT9IbborTtjp3eRGM-01ML3y1L1eeeqVpwbQiWcyvTvmL82I7aPlAWASfDwIMF1553DS0bqVZesmtLNug_t__qcndjs47xLtX7jH2Idl8omfBh25Zvp6_ej6UBCMiaKQ4h-vZ5s7</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1629970754</pqid></control><display><type>article</type><title>Co-existence of Lichen Sclerosus and Localized Scleroderma in Female Monozygotic Twins</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Lis-Święty, Anna, MD, PhD ; Mierzwińska, Katarzyna, MD ; Wodok-Wieczorek, Karolina, MD ; Widuchowska, Małgorzata, MD, PhD ; Brzezińska-Wcisło, Ligia, MD, PhD</creator><creatorcontrib>Lis-Święty, Anna, MD, PhD ; Mierzwińska, Katarzyna, MD ; Wodok-Wieczorek, Karolina, MD ; Widuchowska, Małgorzata, MD, PhD ; Brzezińska-Wcisło, Ligia, MD, PhD</creatorcontrib><description>Abstract Background Etiology of lichen sclerosus (LiS) and localized scleroderma (LoS) is uncertain and probably multifactorial. Case We describe a case of female monozygotic twins who presented co-existence of LiS and LoS. Skin lesions typical for LoS occurred in both patients, at the age of 10. One sister was diagnosed with linear LoS of the lower limb affecting deeper situated subcutaneous tissue and muscles. The other sister was diagnosed with guttate LoS of the trunk, with slow progression of the skin lesions. In both sisters vulvar LiS developed at the age of 19. Conclusions Co-existence of LiS and LoS in monozygotic twins indicates the possible genetic contribution to the pathogenesis of these diseases and the close relationship between them.</description><identifier>ISSN: 1083-3188</identifier><identifier>EISSN: 1873-4332</identifier><identifier>DOI: 10.1016/j.jpag.2013.11.010</identifier><identifier>PMID: 24841519</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Diseases in Twins ; Familial occurrence ; Female ; Humans ; Lichen sclerosus ; Lichen Sclerosus et Atrophicus - complications ; Lichen Sclerosus et Atrophicus - genetics ; Localized scleroderma ; Obstetrics and Gynecology ; Pediatrics ; Scleroderma, Localized - complications ; Scleroderma, Localized - genetics ; Siblings ; Twins, Monozygotic ; Young Adult</subject><ispartof>Journal of pediatric & adolescent gynecology, 2014-12, Vol.27 (6), p.e133-e136</ispartof><rights>North American Society for Pediatric and Adolescent Gynecology</rights><rights>2014 North American Society for Pediatric and Adolescent Gynecology</rights><rights>Copyright © 2014 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c326t-7488ab869d62ee3607580b8f26f2a56f835c1e51e272dbb0f79eab5e99c8d3b33</citedby><cites>FETCH-LOGICAL-c326t-7488ab869d62ee3607580b8f26f2a56f835c1e51e272dbb0f79eab5e99c8d3b33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jpag.2013.11.010$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24841519$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lis-Święty, Anna, MD, PhD</creatorcontrib><creatorcontrib>Mierzwińska, Katarzyna, MD</creatorcontrib><creatorcontrib>Wodok-Wieczorek, Karolina, MD</creatorcontrib><creatorcontrib>Widuchowska, Małgorzata, MD, PhD</creatorcontrib><creatorcontrib>Brzezińska-Wcisło, Ligia, MD, PhD</creatorcontrib><title>Co-existence of Lichen Sclerosus and Localized Scleroderma in Female Monozygotic Twins</title><title>Journal of pediatric & adolescent gynecology</title><addtitle>J Pediatr Adolesc Gynecol</addtitle><description>Abstract Background Etiology of lichen sclerosus (LiS) and localized scleroderma (LoS) is uncertain and probably multifactorial. Case We describe a case of female monozygotic twins who presented co-existence of LiS and LoS. Skin lesions typical for LoS occurred in both patients, at the age of 10. One sister was diagnosed with linear LoS of the lower limb affecting deeper situated subcutaneous tissue and muscles. The other sister was diagnosed with guttate LoS of the trunk, with slow progression of the skin lesions. In both sisters vulvar LiS developed at the age of 19. Conclusions Co-existence of LiS and LoS in monozygotic twins indicates the possible genetic contribution to the pathogenesis of these diseases and the close relationship between them.</description><subject>Diseases in Twins</subject><subject>Familial occurrence</subject><subject>Female</subject><subject>Humans</subject><subject>Lichen sclerosus</subject><subject>Lichen Sclerosus et Atrophicus - complications</subject><subject>Lichen Sclerosus et Atrophicus - genetics</subject><subject>Localized scleroderma</subject><subject>Obstetrics and Gynecology</subject><subject>Pediatrics</subject><subject>Scleroderma, Localized - complications</subject><subject>Scleroderma, Localized - genetics</subject><subject>Siblings</subject><subject>Twins, Monozygotic</subject><subject>Young Adult</subject><issn>1083-3188</issn><issn>1873-4332</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUFv1DAQhS0EoqXwBzggH7kkeOzEcSSEhFaUVtqKQwtXy3EmxSGxlzgpbH89jnbbQw-cZjR672nmG0LeAsuBgfzQ5_3O3OacgcgBcgbsGTkFVYmsEII_Tz1TIhOg1Al5FWPPGKtKqV6SE16oAkqoT8mPTcjwr4szeos0dHTr7E_09NoOOIW4RGp8S7fBmsHdY3uctziNhjpPz3E0A9Kr4MP9_jbMztKbP87H1-RFZ4aIb471jHw__3Kzuci2375ebj5vMyu4nLOqUMo0Stat5IhCpv0Ua1THZcdNKTslSgtYAvKKt03DuqpG05RY11a1ohHijLw_5O6m8HvBOOvRRYvDYDyGJWqQvK6rFFskKT9IbborTtjp3eRGM-01ML3y1L1eeeqVpwbQiWcyvTvmL82I7aPlAWASfDwIMF1553DS0bqVZesmtLNug_t__qcndjs47xLtX7jH2Idl8omfBh25Zvp6_ej6UBCMiaKQ4h-vZ5s7</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Lis-Święty, Anna, MD, PhD</creator><creator>Mierzwińska, Katarzyna, MD</creator><creator>Wodok-Wieczorek, Karolina, MD</creator><creator>Widuchowska, Małgorzata, MD, PhD</creator><creator>Brzezińska-Wcisło, Ligia, MD, PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141201</creationdate><title>Co-existence of Lichen Sclerosus and Localized Scleroderma in Female Monozygotic Twins</title><author>Lis-Święty, Anna, MD, PhD ; Mierzwińska, Katarzyna, MD ; Wodok-Wieczorek, Karolina, MD ; Widuchowska, Małgorzata, MD, PhD ; Brzezińska-Wcisło, Ligia, MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-7488ab869d62ee3607580b8f26f2a56f835c1e51e272dbb0f79eab5e99c8d3b33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Diseases in Twins</topic><topic>Familial occurrence</topic><topic>Female</topic><topic>Humans</topic><topic>Lichen sclerosus</topic><topic>Lichen Sclerosus et Atrophicus - complications</topic><topic>Lichen Sclerosus et Atrophicus - genetics</topic><topic>Localized scleroderma</topic><topic>Obstetrics and Gynecology</topic><topic>Pediatrics</topic><topic>Scleroderma, Localized - complications</topic><topic>Scleroderma, Localized - genetics</topic><topic>Siblings</topic><topic>Twins, Monozygotic</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lis-Święty, Anna, MD, PhD</creatorcontrib><creatorcontrib>Mierzwińska, Katarzyna, MD</creatorcontrib><creatorcontrib>Wodok-Wieczorek, Karolina, MD</creatorcontrib><creatorcontrib>Widuchowska, Małgorzata, MD, PhD</creatorcontrib><creatorcontrib>Brzezińska-Wcisło, Ligia, MD, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pediatric & adolescent gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lis-Święty, Anna, MD, PhD</au><au>Mierzwińska, Katarzyna, MD</au><au>Wodok-Wieczorek, Karolina, MD</au><au>Widuchowska, Małgorzata, MD, PhD</au><au>Brzezińska-Wcisło, Ligia, MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Co-existence of Lichen Sclerosus and Localized Scleroderma in Female Monozygotic Twins</atitle><jtitle>Journal of pediatric & adolescent gynecology</jtitle><addtitle>J Pediatr Adolesc Gynecol</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>27</volume><issue>6</issue><spage>e133</spage><epage>e136</epage><pages>e133-e136</pages><issn>1083-3188</issn><eissn>1873-4332</eissn><abstract>Abstract Background Etiology of lichen sclerosus (LiS) and localized scleroderma (LoS) is uncertain and probably multifactorial. Case We describe a case of female monozygotic twins who presented co-existence of LiS and LoS. Skin lesions typical for LoS occurred in both patients, at the age of 10. One sister was diagnosed with linear LoS of the lower limb affecting deeper situated subcutaneous tissue and muscles. The other sister was diagnosed with guttate LoS of the trunk, with slow progression of the skin lesions. In both sisters vulvar LiS developed at the age of 19. Conclusions Co-existence of LiS and LoS in monozygotic twins indicates the possible genetic contribution to the pathogenesis of these diseases and the close relationship between them.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>24841519</pmid><doi>10.1016/j.jpag.2013.11.010</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1083-3188 |
| ispartof | Journal of pediatric & adolescent gynecology, 2014-12, Vol.27 (6), p.e133-e136 |
| issn | 1083-3188 1873-4332 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1629970754 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Diseases in Twins Familial occurrence Female Humans Lichen sclerosus Lichen Sclerosus et Atrophicus - complications Lichen Sclerosus et Atrophicus - genetics Localized scleroderma Obstetrics and Gynecology Pediatrics Scleroderma, Localized - complications Scleroderma, Localized - genetics Siblings Twins, Monozygotic Young Adult |
| title | Co-existence of Lichen Sclerosus and Localized Scleroderma in Female Monozygotic Twins |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T05%3A31%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Co-existence%20of%20Lichen%20Sclerosus%20and%20Localized%20Scleroderma%20in%20Female%20Monozygotic%20Twins&rft.jtitle=Journal%20of%20pediatric%20&%20adolescent%20gynecology&rft.au=Lis-%C5%9Awi%C4%99ty,%20Anna,%20MD,%20PhD&rft.date=2014-12-01&rft.volume=27&rft.issue=6&rft.spage=e133&rft.epage=e136&rft.pages=e133-e136&rft.issn=1083-3188&rft.eissn=1873-4332&rft_id=info:doi/10.1016/j.jpag.2013.11.010&rft_dat=%3Cproquest_cross%3E1629970754%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1629970754&rft_id=info:pmid/24841519&rft_els_id=S1083318813003446&rfr_iscdi=true |