Effect of Fenoldopam on Use of Renal Replacement Therapy Among Patients With Acute Kidney Injury After Cardiac Surgery: A Randomized Clinical Trial

IMPORTANCE: No effective pharmaceutical agents have yet been identified to treat acute kidney injury after cardiac surgery. OBJECTIVE: To determine whether fenoldopam reduces the need for renal replacement therapy in critically ill cardiac surgery patients with acute kidney injury. DESIGN, SETTING,...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2014-12, Vol.312 (21), p.2244-2253
Hauptverfasser:	Bove, Tiziana, Zangrillo, Alberto, Guarracino, Fabio, Alvaro, Gabriele, Persi, Bruno, Maglioni, Enivarco, Galdieri, Nicola, Comis, Marco, Caramelli, Fabio, Pasero, Daniela C, Pala, Giovanni, Renzini, Massimo, Conte, Massimiliano, Paternoster, Gianluca, Martinez, Blanca, Pinelli, Fulvio, Frontini, Mario, Zucchetti, Maria C, Pappalardo, Federico, Amantea, Bruno, Camata, Annamaria, Pisano, Antonio, Verdecchia, Claudio, Dal Checco, Erika, Cariello, Claudia, Faita, Luana, Baldassarri, Rubia, Scandroglio, Anna M, Saleh, Omar, Lembo, Rosalba, Calabrò, Maria G, Bellomo, Rinaldo, Landoni, Giovanni
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cardiac Surgical Procedures Clinical trials Creatinine Critical Illness Double-Blind Method Drug therapy Drugs Emergency and intensive care: renal failure. Dialysis management Female Fenoldopam - adverse effects Fenoldopam - therapeutic use General aspects Humans Hypotension - chemically induced Intensive care medicine Intensive Care Units Kidney diseases Kidneys Male Medical sciences Middle Aged Mortality Nephrology. Urinary tract diseases Postoperative Complications Renal Replacement Therapy - methods United States Urinary system involvement in other diseases. Miscellaneous Vasodilator Agents - adverse effects Vasodilator Agents - therapeutic use
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