Dietary glycaemic index and glycaemic load in relation to all-cause and cause-specific mortality in a Japanese community: the Takayama study

Diets with a high glycaemic index (GI) or glycaemic load (GL) have been hypothesised to increase the risk of diabetes, CVD and some cancers. In the present study, the associations of dietary GI and GL with the risk of all-cause and cause-specific mortality were prospectively examined in a general po...

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Veröffentlicht in:British journal of nutrition 2014-12, Vol.112 (12), p.2010-2017
Hauptverfasser: Nagata, Chisato, Wada, Keiko, Tsuji, Michiko, Kawachi, Toshiaki, Nakamura, Kozue
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container_end_page 2017
container_issue 12
container_start_page 2010
container_title British journal of nutrition
container_volume 112
creator Nagata, Chisato
Wada, Keiko
Tsuji, Michiko
Kawachi, Toshiaki
Nakamura, Kozue
description Diets with a high glycaemic index (GI) or glycaemic load (GL) have been hypothesised to increase the risk of diabetes, CVD and some cancers. In the present study, the associations of dietary GI and GL with the risk of all-cause and cause-specific mortality were prospectively examined in a general population in Japan, where white rice is the main contributor of dietary GI and GL. A total of 28 356 residents of Takayama City, Japan, who responded to a self-administered questionnaire in 1992 were included in the present analyses. Dietary intake was assessed using a validated FFQ. Mortality was ascertained over 16 years. In men, dietary GI was found to be significantly inversely associated with the risk of all-cause and non-cancer, non-cardiovascular mortality; the hazard ratios (HR) for the highest v. lowest quartile were 0·80 (95 % CI 0·68, 0·95) and 0·64 (95 % CI 0·49, 0·84), respectively. Dietary GL was found to be significantly inversely associated with the risk of all-cause, cancer, and non-cancer, non-cardiovascular mortality; the HR for the highest v. lowest quartile were 0·71 (95 % CI 0·59, 0·86), 0·71 (95 % CI 0·52, 0·99) and 0·64 (95 % CI 0·48, 0·87), respectively. The results obtained for the GL derived from white rice, but not from other foods, closely mirrored those obtained for overall GL. In women, dietary GI was found to be significantly positively associated with the risk of cardiovascular mortality; the HR for the highest v. lowest quartile was 1·56 (95 % CI 1·15, 2·13). The results of the present study suggest potential favourable effects of dietary GI and GL on mortality in men, but an association between high GI and an increased risk of cardiovascular mortality in women.
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subjects Biological and medical sciences
Blood Glucose - metabolism
Cancer
Cardiovascular Diseases - mortality
Cause of Death
Diabetes
Diet
Dietary Surveys and Nutritional Epidemiology
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Glycemic Index
Health risks
Humans
Japan
Male
Middle Aged
Mortality
Neoplasms - mortality
Nutrition
Oryza
Sex Factors
Surveys and Questionnaires
Vertebrates: anatomy and physiology, studies on body, several organs or systems
title Dietary glycaemic index and glycaemic load in relation to all-cause and cause-specific mortality in a Japanese community: the Takayama study
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