Experimental titanium alloys for dental applications
Statement of problem Although the use of titanium has increased, casting difficulties limit routine use. Purpose The purpose of the present study was to compare the mechanical properties and biocompatibility of the experimental titanium alloys titanium–5-zirconium, titanium–5-tantalum, and titanium–...
Gespeichert in:
Veröffentlicht in: | The Journal of prosthetic dentistry 2014-12, Vol.112 (6), p.1448-1460 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 1460 |
---|---|
container_issue | 6 |
container_start_page | 1448 |
container_title | The Journal of prosthetic dentistry |
container_volume | 112 |
creator | Faria, Adriana C.L., DDS, MSc, PhD Rodrigues, Renata C.S., DDS, MSc, PhD Rosa, Adalberto L., DDS, MSc, PhD Ribeiro, Ricardo F., DDS, MSc, PhD |
description | Statement of problem Although the use of titanium has increased, casting difficulties limit routine use. Purpose The purpose of the present study was to compare the mechanical properties and biocompatibility of the experimental titanium alloys titanium–5-zirconium, titanium–5-tantalum, and titanium–5-tantalum–5-zirconium (in wt%) with those of commercially pure titanium. Material and methods Specimens of titanium alloys and commercially pure titanium were cast by using plasma. Their modulus of elasticity and ultimate tensile strength were determined in a universal testing machine. Biocompatibility was evaluated with SCC9 cells. In periods of 1, 4, 7, 10, and 14 days, cell proliferation was evaluated by the (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium reduction assay, and cell viability was evaluated in the 7-day period. Cell morphology was evaluated at 2, 12, and 24 hours. Modulus of elasticity, ultimate tensile strength, and cell viability were analyzed by 1-way ANOVA and the Bonferroni test; cell proliferation data were compared by 2-way ANOVA (alloy versus time) and by the Bonferroni test; and the cell morphology data were analyzed by split-plot design. All statistical tests were performed at the 95% confidence level ( P |
doi_str_mv | 10.1016/j.prosdent.2013.12.025 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1629964920</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S002239131400287X</els_id><sourcerecordid>1629964920</sourcerecordid><originalsourceid>FETCH-LOGICAL-c423t-2ca860e209132f4923a0d0cff1fb845996505851c35802ff629399f404010d983</originalsourceid><addsrcrecordid>eNqFkc1OwzAQhC0EoqXwClWPXBJ27SS1LwhUlR-pEgdA4ma5ji25uEmIE0TfHkelHLhw8kqemdV8S8gUIUXA4mqTNm0dSlN1KQVkKdIUaH5ExghinhQ8w2MyBqA0YQLZiJyFsAEAns_xlIxoDpxTEGOSLb8a07ptDFJ-1rlOVa7fzpT39S7MbN3Oyv2XahrvtOpcXYVzcmKVD-bi552Q17vly-IhWT3dPy5uV4nOKOsSqhUvwMQ9yKjNBGUKStDWol3zLBeiyCHnOWqWc6DWFlQwIWwGGSCUgrMJudznxq4fvQmd3LqgjfeqMnUfJEaHKGIwRGmxl-qIJbTGyia2Uu1OIsiBmNzIAzE5EJNIZSQWjdOfHf16a8pf2wFRFNzsBSY2_XSmlUE7U2lTutboTpa1-3_H9Z8I7V0Vafp3szNhU_dtFTlKlCEa5PNwt-FsmMWJz9_YN9W_k4U</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1629964920</pqid></control><display><type>article</type><title>Experimental titanium alloys for dental applications</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Faria, Adriana C.L., DDS, MSc, PhD ; Rodrigues, Renata C.S., DDS, MSc, PhD ; Rosa, Adalberto L., DDS, MSc, PhD ; Ribeiro, Ricardo F., DDS, MSc, PhD</creator><creatorcontrib>Faria, Adriana C.L., DDS, MSc, PhD ; Rodrigues, Renata C.S., DDS, MSc, PhD ; Rosa, Adalberto L., DDS, MSc, PhD ; Ribeiro, Ricardo F., DDS, MSc, PhD</creatorcontrib><description>Statement of problem Although the use of titanium has increased, casting difficulties limit routine use. Purpose The purpose of the present study was to compare the mechanical properties and biocompatibility of the experimental titanium alloys titanium–5-zirconium, titanium–5-tantalum, and titanium–5-tantalum–5-zirconium (in wt%) with those of commercially pure titanium. Material and methods Specimens of titanium alloys and commercially pure titanium were cast by using plasma. Their modulus of elasticity and ultimate tensile strength were determined in a universal testing machine. Biocompatibility was evaluated with SCC9 cells. In periods of 1, 4, 7, 10, and 14 days, cell proliferation was evaluated by the (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium reduction assay, and cell viability was evaluated in the 7-day period. Cell morphology was evaluated at 2, 12, and 24 hours. Modulus of elasticity, ultimate tensile strength, and cell viability were analyzed by 1-way ANOVA and the Bonferroni test; cell proliferation data were compared by 2-way ANOVA (alloy versus time) and by the Bonferroni test; and the cell morphology data were analyzed by split-plot design. All statistical tests were performed at the 95% confidence level ( P <.05). Results Titanium–5-tantalum presented the lowest modulus of elasticity and ultimate tensile strength, whereas titanium–5-zirconium and titanium–5-tantalum–5-zirconium were statistically similar to commercially pure titanium. Cell proliferation and viability were not affected by any alloy being similar to those observed for commercially pure titanium. No noticeably differences were found in the morphology of cells cultured on any alloy and commercially pure titanium. Conclusion Experimental alloys, especially titanium–5-zirconium and titanium–5-tantalum–5-zirconium, presented promising mechanical results for future studies and clinical applications. In addition, these alloys, evaluated by cell proliferation, viability, and morphology, were found to be biocompatible in vitro.</description><identifier>ISSN: 0022-3913</identifier><identifier>EISSN: 1097-6841</identifier><identifier>DOI: 10.1016/j.prosdent.2013.12.025</identifier><identifier>PMID: 25088209</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Alloys - chemistry ; Alloys - pharmacology ; Biocompatible Materials - chemistry ; Biocompatible Materials - pharmacology ; Cell Line, Tumor ; Cell Proliferation - drug effects ; Cell Shape - drug effects ; Cell Survival - drug effects ; Dental Alloys - chemistry ; Dental Alloys - pharmacology ; Dental Casting Technique ; Dental Materials - chemistry ; Dental Materials - pharmacology ; Dental Stress Analysis - instrumentation ; Dentistry ; Elastic Modulus ; Humans ; Materials Testing ; Mechanical Phenomena ; Microscopy, Electron, Scanning ; Plasma Gases ; Pliability ; Tantalum - chemistry ; Tantalum - pharmacology ; Tensile Strength ; Tetrazolium Salts ; Thiazoles ; Time Factors ; Titanium - chemistry ; Titanium - pharmacology</subject><ispartof>The Journal of prosthetic dentistry, 2014-12, Vol.112 (6), p.1448-1460</ispartof><rights>Editorial Council for the Journal of Prosthetic Dentistry</rights><rights>2014 Editorial Council for the Journal of Prosthetic Dentistry</rights><rights>Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-2ca860e209132f4923a0d0cff1fb845996505851c35802ff629399f404010d983</citedby><cites>FETCH-LOGICAL-c423t-2ca860e209132f4923a0d0cff1fb845996505851c35802ff629399f404010d983</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.prosdent.2013.12.025$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27911,27912,45982</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25088209$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Faria, Adriana C.L., DDS, MSc, PhD</creatorcontrib><creatorcontrib>Rodrigues, Renata C.S., DDS, MSc, PhD</creatorcontrib><creatorcontrib>Rosa, Adalberto L., DDS, MSc, PhD</creatorcontrib><creatorcontrib>Ribeiro, Ricardo F., DDS, MSc, PhD</creatorcontrib><title>Experimental titanium alloys for dental applications</title><title>The Journal of prosthetic dentistry</title><addtitle>J Prosthet Dent</addtitle><description>Statement of problem Although the use of titanium has increased, casting difficulties limit routine use. Purpose The purpose of the present study was to compare the mechanical properties and biocompatibility of the experimental titanium alloys titanium–5-zirconium, titanium–5-tantalum, and titanium–5-tantalum–5-zirconium (in wt%) with those of commercially pure titanium. Material and methods Specimens of titanium alloys and commercially pure titanium were cast by using plasma. Their modulus of elasticity and ultimate tensile strength were determined in a universal testing machine. Biocompatibility was evaluated with SCC9 cells. In periods of 1, 4, 7, 10, and 14 days, cell proliferation was evaluated by the (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium reduction assay, and cell viability was evaluated in the 7-day period. Cell morphology was evaluated at 2, 12, and 24 hours. Modulus of elasticity, ultimate tensile strength, and cell viability were analyzed by 1-way ANOVA and the Bonferroni test; cell proliferation data were compared by 2-way ANOVA (alloy versus time) and by the Bonferroni test; and the cell morphology data were analyzed by split-plot design. All statistical tests were performed at the 95% confidence level ( P <.05). Results Titanium–5-tantalum presented the lowest modulus of elasticity and ultimate tensile strength, whereas titanium–5-zirconium and titanium–5-tantalum–5-zirconium were statistically similar to commercially pure titanium. Cell proliferation and viability were not affected by any alloy being similar to those observed for commercially pure titanium. No noticeably differences were found in the morphology of cells cultured on any alloy and commercially pure titanium. Conclusion Experimental alloys, especially titanium–5-zirconium and titanium–5-tantalum–5-zirconium, presented promising mechanical results for future studies and clinical applications. In addition, these alloys, evaluated by cell proliferation, viability, and morphology, were found to be biocompatible in vitro.</description><subject>Alloys - chemistry</subject><subject>Alloys - pharmacology</subject><subject>Biocompatible Materials - chemistry</subject><subject>Biocompatible Materials - pharmacology</subject><subject>Cell Line, Tumor</subject><subject>Cell Proliferation - drug effects</subject><subject>Cell Shape - drug effects</subject><subject>Cell Survival - drug effects</subject><subject>Dental Alloys - chemistry</subject><subject>Dental Alloys - pharmacology</subject><subject>Dental Casting Technique</subject><subject>Dental Materials - chemistry</subject><subject>Dental Materials - pharmacology</subject><subject>Dental Stress Analysis - instrumentation</subject><subject>Dentistry</subject><subject>Elastic Modulus</subject><subject>Humans</subject><subject>Materials Testing</subject><subject>Mechanical Phenomena</subject><subject>Microscopy, Electron, Scanning</subject><subject>Plasma Gases</subject><subject>Pliability</subject><subject>Tantalum - chemistry</subject><subject>Tantalum - pharmacology</subject><subject>Tensile Strength</subject><subject>Tetrazolium Salts</subject><subject>Thiazoles</subject><subject>Time Factors</subject><subject>Titanium - chemistry</subject><subject>Titanium - pharmacology</subject><issn>0022-3913</issn><issn>1097-6841</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1OwzAQhC0EoqXwClWPXBJ27SS1LwhUlR-pEgdA4ma5ji25uEmIE0TfHkelHLhw8kqemdV8S8gUIUXA4mqTNm0dSlN1KQVkKdIUaH5ExghinhQ8w2MyBqA0YQLZiJyFsAEAns_xlIxoDpxTEGOSLb8a07ptDFJ-1rlOVa7fzpT39S7MbN3Oyv2XahrvtOpcXYVzcmKVD-bi552Q17vly-IhWT3dPy5uV4nOKOsSqhUvwMQ9yKjNBGUKStDWol3zLBeiyCHnOWqWc6DWFlQwIWwGGSCUgrMJudznxq4fvQmd3LqgjfeqMnUfJEaHKGIwRGmxl-qIJbTGyia2Uu1OIsiBmNzIAzE5EJNIZSQWjdOfHf16a8pf2wFRFNzsBSY2_XSmlUE7U2lTutboTpa1-3_H9Z8I7V0Vafp3szNhU_dtFTlKlCEa5PNwt-FsmMWJz9_YN9W_k4U</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Faria, Adriana C.L., DDS, MSc, PhD</creator><creator>Rodrigues, Renata C.S., DDS, MSc, PhD</creator><creator>Rosa, Adalberto L., DDS, MSc, PhD</creator><creator>Ribeiro, Ricardo F., DDS, MSc, PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141201</creationdate><title>Experimental titanium alloys for dental applications</title><author>Faria, Adriana C.L., DDS, MSc, PhD ; Rodrigues, Renata C.S., DDS, MSc, PhD ; Rosa, Adalberto L., DDS, MSc, PhD ; Ribeiro, Ricardo F., DDS, MSc, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-2ca860e209132f4923a0d0cff1fb845996505851c35802ff629399f404010d983</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Alloys - chemistry</topic><topic>Alloys - pharmacology</topic><topic>Biocompatible Materials - chemistry</topic><topic>Biocompatible Materials - pharmacology</topic><topic>Cell Line, Tumor</topic><topic>Cell Proliferation - drug effects</topic><topic>Cell Shape - drug effects</topic><topic>Cell Survival - drug effects</topic><topic>Dental Alloys - chemistry</topic><topic>Dental Alloys - pharmacology</topic><topic>Dental Casting Technique</topic><topic>Dental Materials - chemistry</topic><topic>Dental Materials - pharmacology</topic><topic>Dental Stress Analysis - instrumentation</topic><topic>Dentistry</topic><topic>Elastic Modulus</topic><topic>Humans</topic><topic>Materials Testing</topic><topic>Mechanical Phenomena</topic><topic>Microscopy, Electron, Scanning</topic><topic>Plasma Gases</topic><topic>Pliability</topic><topic>Tantalum - chemistry</topic><topic>Tantalum - pharmacology</topic><topic>Tensile Strength</topic><topic>Tetrazolium Salts</topic><topic>Thiazoles</topic><topic>Time Factors</topic><topic>Titanium - chemistry</topic><topic>Titanium - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Faria, Adriana C.L., DDS, MSc, PhD</creatorcontrib><creatorcontrib>Rodrigues, Renata C.S., DDS, MSc, PhD</creatorcontrib><creatorcontrib>Rosa, Adalberto L., DDS, MSc, PhD</creatorcontrib><creatorcontrib>Ribeiro, Ricardo F., DDS, MSc, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of prosthetic dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Faria, Adriana C.L., DDS, MSc, PhD</au><au>Rodrigues, Renata C.S., DDS, MSc, PhD</au><au>Rosa, Adalberto L., DDS, MSc, PhD</au><au>Ribeiro, Ricardo F., DDS, MSc, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Experimental titanium alloys for dental applications</atitle><jtitle>The Journal of prosthetic dentistry</jtitle><addtitle>J Prosthet Dent</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>112</volume><issue>6</issue><spage>1448</spage><epage>1460</epage><pages>1448-1460</pages><issn>0022-3913</issn><eissn>1097-6841</eissn><abstract>Statement of problem Although the use of titanium has increased, casting difficulties limit routine use. Purpose The purpose of the present study was to compare the mechanical properties and biocompatibility of the experimental titanium alloys titanium–5-zirconium, titanium–5-tantalum, and titanium–5-tantalum–5-zirconium (in wt%) with those of commercially pure titanium. Material and methods Specimens of titanium alloys and commercially pure titanium were cast by using plasma. Their modulus of elasticity and ultimate tensile strength were determined in a universal testing machine. Biocompatibility was evaluated with SCC9 cells. In periods of 1, 4, 7, 10, and 14 days, cell proliferation was evaluated by the (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium reduction assay, and cell viability was evaluated in the 7-day period. Cell morphology was evaluated at 2, 12, and 24 hours. Modulus of elasticity, ultimate tensile strength, and cell viability were analyzed by 1-way ANOVA and the Bonferroni test; cell proliferation data were compared by 2-way ANOVA (alloy versus time) and by the Bonferroni test; and the cell morphology data were analyzed by split-plot design. All statistical tests were performed at the 95% confidence level ( P <.05). Results Titanium–5-tantalum presented the lowest modulus of elasticity and ultimate tensile strength, whereas titanium–5-zirconium and titanium–5-tantalum–5-zirconium were statistically similar to commercially pure titanium. Cell proliferation and viability were not affected by any alloy being similar to those observed for commercially pure titanium. No noticeably differences were found in the morphology of cells cultured on any alloy and commercially pure titanium. Conclusion Experimental alloys, especially titanium–5-zirconium and titanium–5-tantalum–5-zirconium, presented promising mechanical results for future studies and clinical applications. In addition, these alloys, evaluated by cell proliferation, viability, and morphology, were found to be biocompatible in vitro.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25088209</pmid><doi>10.1016/j.prosdent.2013.12.025</doi><tpages>13</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0022-3913 |
ispartof | The Journal of prosthetic dentistry, 2014-12, Vol.112 (6), p.1448-1460 |
issn | 0022-3913 1097-6841 |
language | eng |
recordid | cdi_proquest_miscellaneous_1629964920 |
source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Alloys - chemistry Alloys - pharmacology Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Cell Line, Tumor Cell Proliferation - drug effects Cell Shape - drug effects Cell Survival - drug effects Dental Alloys - chemistry Dental Alloys - pharmacology Dental Casting Technique Dental Materials - chemistry Dental Materials - pharmacology Dental Stress Analysis - instrumentation Dentistry Elastic Modulus Humans Materials Testing Mechanical Phenomena Microscopy, Electron, Scanning Plasma Gases Pliability Tantalum - chemistry Tantalum - pharmacology Tensile Strength Tetrazolium Salts Thiazoles Time Factors Titanium - chemistry Titanium - pharmacology |
title | Experimental titanium alloys for dental applications |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T22%3A07%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Experimental%20titanium%20alloys%20for%20dental%20applications&rft.jtitle=The%20Journal%20of%20prosthetic%20dentistry&rft.au=Faria,%20Adriana%20C.L.,%20DDS,%20MSc,%20PhD&rft.date=2014-12-01&rft.volume=112&rft.issue=6&rft.spage=1448&rft.epage=1460&rft.pages=1448-1460&rft.issn=0022-3913&rft.eissn=1097-6841&rft_id=info:doi/10.1016/j.prosdent.2013.12.025&rft_dat=%3Cproquest_cross%3E1629964920%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1629964920&rft_id=info:pmid/25088209&rft_els_id=S002239131400287X&rfr_iscdi=true |