Translating Human Genetics into Novel Treatment Targets for Schizophrenia

Human genetics is a rational starting point for target identification in drug discovery, yet this approach has found little application in neuroscience. Recent large-scale analyses have begun to identify robust genetic loci for schizophrenia, providing an opportunity to derive novel drug targets. He...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2014-11, Vol.84 (3), p.537-541
Hauptverfasser:	Schubert, Christian R., Xi, Hualin S., Wendland, Jens R., O’Donnell, Patricio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drug Discovery Genetic Predisposition to Disease Genetics Genetics, Medical Genomics Humans Pharmaceutical industry R&D Research & development Schizophrenia - genetics Schizophrenia - therapy Translational Medical Research - methods
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