Anthropometric Indices Are Not Satisfactory Predictors of Metabolic Comorbidities in Obese Children and Adolescents

Objective To assess the accuracy of body mass index (BMI), Z score of the BMI, waist circumference, and waist-to-height ratio in selecting obese children with fasting metabolic impairments or impaired glucose tolerance. Study design In a cohort of 883 obese children and adolescents (age 8-18 years),...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Journal of pediatrics 2014-12, Vol.165 (6), p.1178-1183.e2
Hauptverfasser: Morandi, Anita, MD, PhD, Miraglia del Giudice, Emanuele, MD, Martino, Francesco, MD, Martino, Eliana, MD, Bozzola, Mauro, MD, Maffeis, Claudio, MD
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1183.e2
container_issue 6
container_start_page 1178
container_title The Journal of pediatrics
container_volume 165
creator Morandi, Anita, MD, PhD
Miraglia del Giudice, Emanuele, MD
Martino, Francesco, MD
Martino, Eliana, MD
Bozzola, Mauro, MD
Maffeis, Claudio, MD
description Objective To assess the accuracy of body mass index (BMI), Z score of the BMI, waist circumference, and waist-to-height ratio in selecting obese children with fasting metabolic impairments or impaired glucose tolerance. Study design In a cohort of 883 obese children and adolescents (age 8-18 years), we assessed the associations of anthropometric indices with traditional metabolic complications of obesity (impaired fasting glucose, impaired glucose tolerance, hypertension, high triglycerides, low high-density lipoprotein-cholesterol). The accuracy of anthropometric indices as markers of metabolic impairment was assessed by receiver operating characteristic analysis and the areas under the receiver operating characteristics curves (AUROCs) of anthropometric indices were compared with each other by the DeLong test. Results BMI, Z score of the BMI, waist circumference, and waist-to-height ratio were associated with metabolic impairments but showed low to moderate accuracy in discriminating both single and clustered metabolic impairments. The AUROCs ranged from 0.55-0.70. The 4 anthropometric indices did not show significantly different AUROCs as predictors of clustered metabolic risk factors (all P values of DeLong tests: >.05). Conclusions Commonly used anthropometric indices are not satisfactory markers of metabolic comorbidity among obese children and adolescents and should not be adopted as screening tools for the metabolic assessment of this category of patients.
doi_str_mv 10.1016/j.jpeds.2014.07.004
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1629962043</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S002234761400626X</els_id><sourcerecordid>1629962043</sourcerecordid><originalsourceid>FETCH-LOGICAL-c484t-4ac09e2b4a1e6218b8037b42c33c35be066d025073d23343a3444915bcd910ea3</originalsourceid><addsrcrecordid>eNqFkc1uEzEUhS1ERUPLEyAhL9nMcP0TT2YBUhTxU6m0lQoSO8tj36geZuxgO0h5exxSWLBhZUs-n6_9HUJeMmgZMPVmbMcdutxyYLKFrgWQT8iCQd81aiXEU7IA4LwRslPn5HnOIwD0EuAZOedLxrjq2YLkdSgPKe7ijCV5S6-C8xYzXSekN7HQe1N83hpbYjrQu4T1tG4zjVv6GYsZ4lShTZxjGrzzxVfUB3o7YEa6efCTSxioCY6uXZwwWwwlX5KzrZkyvnhcL8jXD--_bD4117cfrzbr68bKlSyNNBZ65IM0DBVnq2EFohskt0JYsRwQlHLAl9AJx4WQwggpZc-Wg3U9AzTigrw-3btL8ccec9Gzry-YJhMw7rNmive94iBFjYpT1KaYc8Kt3iU_m3TQDPTRth71b9v6aFtDp6vtSr16HLAfZnR_mT96a-DtKYD1mz89Jp2tx2CrxoS2aBf9fwa8-4e3kw_emuk7HjCPcZ9CNaiZzlyDvj8Wfuyb1ZoVV9_EL6qoprw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1629962043</pqid></control><display><type>article</type><title>Anthropometric Indices Are Not Satisfactory Predictors of Metabolic Comorbidities in Obese Children and Adolescents</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Morandi, Anita, MD, PhD ; Miraglia del Giudice, Emanuele, MD ; Martino, Francesco, MD ; Martino, Eliana, MD ; Bozzola, Mauro, MD ; Maffeis, Claudio, MD</creator><creatorcontrib>Morandi, Anita, MD, PhD ; Miraglia del Giudice, Emanuele, MD ; Martino, Francesco, MD ; Martino, Eliana, MD ; Bozzola, Mauro, MD ; Maffeis, Claudio, MD</creatorcontrib><description>Objective To assess the accuracy of body mass index (BMI), Z score of the BMI, waist circumference, and waist-to-height ratio in selecting obese children with fasting metabolic impairments or impaired glucose tolerance. Study design In a cohort of 883 obese children and adolescents (age 8-18 years), we assessed the associations of anthropometric indices with traditional metabolic complications of obesity (impaired fasting glucose, impaired glucose tolerance, hypertension, high triglycerides, low high-density lipoprotein-cholesterol). The accuracy of anthropometric indices as markers of metabolic impairment was assessed by receiver operating characteristic analysis and the areas under the receiver operating characteristics curves (AUROCs) of anthropometric indices were compared with each other by the DeLong test. Results BMI, Z score of the BMI, waist circumference, and waist-to-height ratio were associated with metabolic impairments but showed low to moderate accuracy in discriminating both single and clustered metabolic impairments. The AUROCs ranged from 0.55-0.70. The 4 anthropometric indices did not show significantly different AUROCs as predictors of clustered metabolic risk factors (all P values of DeLong tests: &gt;.05). Conclusions Commonly used anthropometric indices are not satisfactory markers of metabolic comorbidity among obese children and adolescents and should not be adopted as screening tools for the metabolic assessment of this category of patients.</description><identifier>ISSN: 0022-3476</identifier><identifier>EISSN: 1097-6833</identifier><identifier>DOI: 10.1016/j.jpeds.2014.07.004</identifier><identifier>PMID: 25112691</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Child ; Comorbidity ; Humans ; Metabolic Syndrome - epidemiology ; Obesity - epidemiology ; Pediatrics ; ROC Curve ; Triglycerides - blood ; Waist Circumference ; Waist-Height Ratio</subject><ispartof>The Journal of pediatrics, 2014-12, Vol.165 (6), p.1178-1183.e2</ispartof><rights>Elsevier Inc.</rights><rights>2014 Elsevier Inc.</rights><rights>Copyright © 2014 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c484t-4ac09e2b4a1e6218b8037b42c33c35be066d025073d23343a3444915bcd910ea3</citedby><cites>FETCH-LOGICAL-c484t-4ac09e2b4a1e6218b8037b42c33c35be066d025073d23343a3444915bcd910ea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jpeds.2014.07.004$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25112691$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Morandi, Anita, MD, PhD</creatorcontrib><creatorcontrib>Miraglia del Giudice, Emanuele, MD</creatorcontrib><creatorcontrib>Martino, Francesco, MD</creatorcontrib><creatorcontrib>Martino, Eliana, MD</creatorcontrib><creatorcontrib>Bozzola, Mauro, MD</creatorcontrib><creatorcontrib>Maffeis, Claudio, MD</creatorcontrib><title>Anthropometric Indices Are Not Satisfactory Predictors of Metabolic Comorbidities in Obese Children and Adolescents</title><title>The Journal of pediatrics</title><addtitle>J Pediatr</addtitle><description>Objective To assess the accuracy of body mass index (BMI), Z score of the BMI, waist circumference, and waist-to-height ratio in selecting obese children with fasting metabolic impairments or impaired glucose tolerance. Study design In a cohort of 883 obese children and adolescents (age 8-18 years), we assessed the associations of anthropometric indices with traditional metabolic complications of obesity (impaired fasting glucose, impaired glucose tolerance, hypertension, high triglycerides, low high-density lipoprotein-cholesterol). The accuracy of anthropometric indices as markers of metabolic impairment was assessed by receiver operating characteristic analysis and the areas under the receiver operating characteristics curves (AUROCs) of anthropometric indices were compared with each other by the DeLong test. Results BMI, Z score of the BMI, waist circumference, and waist-to-height ratio were associated with metabolic impairments but showed low to moderate accuracy in discriminating both single and clustered metabolic impairments. The AUROCs ranged from 0.55-0.70. The 4 anthropometric indices did not show significantly different AUROCs as predictors of clustered metabolic risk factors (all P values of DeLong tests: &gt;.05). Conclusions Commonly used anthropometric indices are not satisfactory markers of metabolic comorbidity among obese children and adolescents and should not be adopted as screening tools for the metabolic assessment of this category of patients.</description><subject>Adolescent</subject><subject>Child</subject><subject>Comorbidity</subject><subject>Humans</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Obesity - epidemiology</subject><subject>Pediatrics</subject><subject>ROC Curve</subject><subject>Triglycerides - blood</subject><subject>Waist Circumference</subject><subject>Waist-Height Ratio</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1uEzEUhS1ERUPLEyAhL9nMcP0TT2YBUhTxU6m0lQoSO8tj36geZuxgO0h5exxSWLBhZUs-n6_9HUJeMmgZMPVmbMcdutxyYLKFrgWQT8iCQd81aiXEU7IA4LwRslPn5HnOIwD0EuAZOedLxrjq2YLkdSgPKe7ijCV5S6-C8xYzXSekN7HQe1N83hpbYjrQu4T1tG4zjVv6GYsZ4lShTZxjGrzzxVfUB3o7YEa6efCTSxioCY6uXZwwWwwlX5KzrZkyvnhcL8jXD--_bD4117cfrzbr68bKlSyNNBZ65IM0DBVnq2EFohskt0JYsRwQlHLAl9AJx4WQwggpZc-Wg3U9AzTigrw-3btL8ccec9Gzry-YJhMw7rNmive94iBFjYpT1KaYc8Kt3iU_m3TQDPTRth71b9v6aFtDp6vtSr16HLAfZnR_mT96a-DtKYD1mz89Jp2tx2CrxoS2aBf9fwa8-4e3kw_emuk7HjCPcZ9CNaiZzlyDvj8Wfuyb1ZoVV9_EL6qoprw</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Morandi, Anita, MD, PhD</creator><creator>Miraglia del Giudice, Emanuele, MD</creator><creator>Martino, Francesco, MD</creator><creator>Martino, Eliana, MD</creator><creator>Bozzola, Mauro, MD</creator><creator>Maffeis, Claudio, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141201</creationdate><title>Anthropometric Indices Are Not Satisfactory Predictors of Metabolic Comorbidities in Obese Children and Adolescents</title><author>Morandi, Anita, MD, PhD ; Miraglia del Giudice, Emanuele, MD ; Martino, Francesco, MD ; Martino, Eliana, MD ; Bozzola, Mauro, MD ; Maffeis, Claudio, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-4ac09e2b4a1e6218b8037b42c33c35be066d025073d23343a3444915bcd910ea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Child</topic><topic>Comorbidity</topic><topic>Humans</topic><topic>Metabolic Syndrome - epidemiology</topic><topic>Obesity - epidemiology</topic><topic>Pediatrics</topic><topic>ROC Curve</topic><topic>Triglycerides - blood</topic><topic>Waist Circumference</topic><topic>Waist-Height Ratio</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Morandi, Anita, MD, PhD</creatorcontrib><creatorcontrib>Miraglia del Giudice, Emanuele, MD</creatorcontrib><creatorcontrib>Martino, Francesco, MD</creatorcontrib><creatorcontrib>Martino, Eliana, MD</creatorcontrib><creatorcontrib>Bozzola, Mauro, MD</creatorcontrib><creatorcontrib>Maffeis, Claudio, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Morandi, Anita, MD, PhD</au><au>Miraglia del Giudice, Emanuele, MD</au><au>Martino, Francesco, MD</au><au>Martino, Eliana, MD</au><au>Bozzola, Mauro, MD</au><au>Maffeis, Claudio, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anthropometric Indices Are Not Satisfactory Predictors of Metabolic Comorbidities in Obese Children and Adolescents</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>165</volume><issue>6</issue><spage>1178</spage><epage>1183.e2</epage><pages>1178-1183.e2</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><abstract>Objective To assess the accuracy of body mass index (BMI), Z score of the BMI, waist circumference, and waist-to-height ratio in selecting obese children with fasting metabolic impairments or impaired glucose tolerance. Study design In a cohort of 883 obese children and adolescents (age 8-18 years), we assessed the associations of anthropometric indices with traditional metabolic complications of obesity (impaired fasting glucose, impaired glucose tolerance, hypertension, high triglycerides, low high-density lipoprotein-cholesterol). The accuracy of anthropometric indices as markers of metabolic impairment was assessed by receiver operating characteristic analysis and the areas under the receiver operating characteristics curves (AUROCs) of anthropometric indices were compared with each other by the DeLong test. Results BMI, Z score of the BMI, waist circumference, and waist-to-height ratio were associated with metabolic impairments but showed low to moderate accuracy in discriminating both single and clustered metabolic impairments. The AUROCs ranged from 0.55-0.70. The 4 anthropometric indices did not show significantly different AUROCs as predictors of clustered metabolic risk factors (all P values of DeLong tests: &gt;.05). Conclusions Commonly used anthropometric indices are not satisfactory markers of metabolic comorbidity among obese children and adolescents and should not be adopted as screening tools for the metabolic assessment of this category of patients.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25112691</pmid><doi>10.1016/j.jpeds.2014.07.004</doi></addata></record>
fulltext fulltext
identifier ISSN: 0022-3476
ispartof The Journal of pediatrics, 2014-12, Vol.165 (6), p.1178-1183.e2
issn 0022-3476
1097-6833
language eng
recordid cdi_proquest_miscellaneous_1629962043
source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Adolescent
Child
Comorbidity
Humans
Metabolic Syndrome - epidemiology
Obesity - epidemiology
Pediatrics
ROC Curve
Triglycerides - blood
Waist Circumference
Waist-Height Ratio
title Anthropometric Indices Are Not Satisfactory Predictors of Metabolic Comorbidities in Obese Children and Adolescents
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T15%3A11%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Anthropometric%20Indices%20Are%20Not%20Satisfactory%20Predictors%20of%20Metabolic%20Comorbidities%20in%20Obese%20Children%20and%20Adolescents&rft.jtitle=The%20Journal%20of%20pediatrics&rft.au=Morandi,%20Anita,%20MD,%20PhD&rft.date=2014-12-01&rft.volume=165&rft.issue=6&rft.spage=1178&rft.epage=1183.e2&rft.pages=1178-1183.e2&rft.issn=0022-3476&rft.eissn=1097-6833&rft_id=info:doi/10.1016/j.jpeds.2014.07.004&rft_dat=%3Cproquest_cross%3E1629962043%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1629962043&rft_id=info:pmid/25112691&rft_els_id=S002234761400626X&rfr_iscdi=true