Psychosocial/survivorship issues in breast cancer: are we doing better?
Modern breast cancer treatment offers many women greater prospects of cure or lengthier, good quality survival than was possible in the past. Advances include improved diagnostic and staging procedures, sophisticated onco-plastic surgery, enhanced radiotherapy techniques, and targeted systemic thera...
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Veröffentlicht in: | JNCI : Journal of the National Cancer Institute 2015-01, Vol.107 (1), p.335-dju335 |
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description | Modern breast cancer treatment offers many women greater prospects of cure or lengthier, good quality survival than was possible in the past. Advances include improved diagnostic and staging procedures, sophisticated onco-plastic surgery, enhanced radiotherapy techniques, and targeted systemic therapies. Much more attention has also been paid to cancer care delivery and access to specialist nurses, counsellors, support groups, and services provided by breast cancer charities. However, there are some concerns that these considerable improvements in treatment delivery and clinical outcomes have not led to similar benefits in the psychosocial, functional, and sexual well-being of women. The impact that non-life threatening, long-term iatrogenic harms of otherwise efficacious anticancer treatments has on patients is often overlooked; this is in part because of the emphasis given to physician-reported safety data in trials and the general exclusion of patient-reported outcomes (PROs). A failure to utilise reliable PRO measures has meant that some problems are underreported, which consequently has hampered much-needed research into ameliorative interventions. Systematic monitoring of quality of life-threatening side effects would permit early implementation of effective interventions and enhance long-term survivorship. Some examples of the pervasive difficulties that continue to affect survivors and evidence that certain interventions might help are provided in this commentary. |
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Advances include improved diagnostic and staging procedures, sophisticated onco-plastic surgery, enhanced radiotherapy techniques, and targeted systemic therapies. Much more attention has also been paid to cancer care delivery and access to specialist nurses, counsellors, support groups, and services provided by breast cancer charities. However, there are some concerns that these considerable improvements in treatment delivery and clinical outcomes have not led to similar benefits in the psychosocial, functional, and sexual well-being of women. The impact that non-life threatening, long-term iatrogenic harms of otherwise efficacious anticancer treatments has on patients is often overlooked; this is in part because of the emphasis given to physician-reported safety data in trials and the general exclusion of patient-reported outcomes (PROs). A failure to utilise reliable PRO measures has meant that some problems are underreported, which consequently has hampered much-needed research into ameliorative interventions. Systematic monitoring of quality of life-threatening side effects would permit early implementation of effective interventions and enhance long-term survivorship. Some examples of the pervasive difficulties that continue to affect survivors and evidence that certain interventions might help are provided in this commentary.</description><identifier>ISSN: 0027-8874</identifier><identifier>EISSN: 1460-2105</identifier><identifier>DOI: 10.1093/jnci/dju335</identifier><identifier>PMID: 25432407</identifier><identifier>CODEN: JNCIEQ</identifier><language>eng</language><publisher>United States: Oxford Publishing Limited (England)</publisher><subject>Affective Symptoms - etiology ; Antineoplastic Agents, Hormonal - adverse effects ; Antineoplastic Combined Chemotherapy Protocols - adverse effects ; Anxiety - etiology ; Breast cancer ; Breast Neoplasms - pathology ; Breast Neoplasms - psychology ; Breast Neoplasms - therapy ; Case-Control Studies ; Cognitive Dysfunction - etiology ; Communication ; Depression - etiology ; Dyspareunia - etiology ; Evidence-Based Medicine ; Fatigue - etiology ; Female ; Health Status ; Humans ; Iatrogenic Disease ; Intervention ; Lymphedema - etiology ; Medical treatment ; Neoplasm Recurrence, Local - psychology ; Physician-Patient Relations ; Practice Guidelines as Topic ; Quality Indicators, Health Care ; Quality of Life ; Randomized Controlled Trials as Topic ; Risk Assessment ; Stress, Psychological - epidemiology ; Stress, Psychological - etiology ; Stress, Psychological - prevention & control ; Stress, Psychological - therapy ; Survivors - psychology ; Survivors - statistics & numerical data ; Vasomotor System - drug effects ; Vasomotor System - physiopathology ; Womens health</subject><ispartof>JNCI : Journal of the National Cancer Institute, 2015-01, Vol.107 (1), p.335-dju335</ispartof><rights>The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.</rights><rights>Copyright Oxford Publishing Limited(England) Jan 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c354t-f91657f3ec664ab79ac98a008bd3579e6a0c9a4f40fb05ea27f9ba4759944e413</citedby><cites>FETCH-LOGICAL-c354t-f91657f3ec664ab79ac98a008bd3579e6a0c9a4f40fb05ea27f9ba4759944e413</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25432407$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fallowfield, Lesley</creatorcontrib><creatorcontrib>Jenkins, Valerie</creatorcontrib><title>Psychosocial/survivorship issues in breast cancer: are we doing better?</title><title>JNCI : Journal of the National Cancer Institute</title><addtitle>J Natl Cancer Inst</addtitle><description>Modern breast cancer treatment offers many women greater prospects of cure or lengthier, good quality survival than was possible in the past. Advances include improved diagnostic and staging procedures, sophisticated onco-plastic surgery, enhanced radiotherapy techniques, and targeted systemic therapies. Much more attention has also been paid to cancer care delivery and access to specialist nurses, counsellors, support groups, and services provided by breast cancer charities. However, there are some concerns that these considerable improvements in treatment delivery and clinical outcomes have not led to similar benefits in the psychosocial, functional, and sexual well-being of women. The impact that non-life threatening, long-term iatrogenic harms of otherwise efficacious anticancer treatments has on patients is often overlooked; this is in part because of the emphasis given to physician-reported safety data in trials and the general exclusion of patient-reported outcomes (PROs). A failure to utilise reliable PRO measures has meant that some problems are underreported, which consequently has hampered much-needed research into ameliorative interventions. Systematic monitoring of quality of life-threatening side effects would permit early implementation of effective interventions and enhance long-term survivorship. Some examples of the pervasive difficulties that continue to affect survivors and evidence that certain interventions might help are provided in this commentary.</description><subject>Affective Symptoms - etiology</subject><subject>Antineoplastic Agents, Hormonal - adverse effects</subject><subject>Antineoplastic Combined Chemotherapy Protocols - adverse effects</subject><subject>Anxiety - etiology</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - pathology</subject><subject>Breast Neoplasms - psychology</subject><subject>Breast Neoplasms - therapy</subject><subject>Case-Control Studies</subject><subject>Cognitive Dysfunction - etiology</subject><subject>Communication</subject><subject>Depression - etiology</subject><subject>Dyspareunia - etiology</subject><subject>Evidence-Based Medicine</subject><subject>Fatigue - etiology</subject><subject>Female</subject><subject>Health Status</subject><subject>Humans</subject><subject>Iatrogenic Disease</subject><subject>Intervention</subject><subject>Lymphedema - etiology</subject><subject>Medical treatment</subject><subject>Neoplasm Recurrence, Local - psychology</subject><subject>Physician-Patient Relations</subject><subject>Practice Guidelines as Topic</subject><subject>Quality Indicators, Health Care</subject><subject>Quality of Life</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Risk Assessment</subject><subject>Stress, Psychological - epidemiology</subject><subject>Stress, Psychological - etiology</subject><subject>Stress, Psychological - prevention & control</subject><subject>Stress, Psychological - therapy</subject><subject>Survivors - psychology</subject><subject>Survivors - statistics & numerical data</subject><subject>Vasomotor System - drug effects</subject><subject>Vasomotor System - physiopathology</subject><subject>Womens health</subject><issn>0027-8874</issn><issn>1460-2105</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0M1LwzAYBvAgipvTk3cJeBGkLs1Hk3gRGTqFgR70XNL0rUvpmpm0k_33dkw9-F7ey4-Hhweh85TcpESzad1aNy3rnjFxgMYpz0hCUyIO0ZgQKhOlJB-hkxhrMpym_BiNqOCMciLHaP4at3bpo7fONNPYh43b-BCXbo1djD1E7FpcBDCxw9a0FsItNgHwF-DSu_YDF9B1EO5O0VFlmghnP3-C3h8f3mZPyeJl_jy7XySWCd4llU4zISsGNsu4KaQ2VitDiCpKJqSGzBCrDa84qQoiwFBZ6cJwKbTmHHjKJuhqn7sO_nOo1-UrFy00jWnB9zFPM6qFEpTJgV7-o7XvQzu0GxRXWmnK1KCu98oGH2OAKl8HtzJhm6ck3-2b7_bN9_sO-uInsy9WUP7Z30HZN47_dqg</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Fallowfield, Lesley</creator><creator>Jenkins, Valerie</creator><general>Oxford Publishing Limited (England)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TO</scope><scope>7U7</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20150101</creationdate><title>Psychosocial/survivorship issues in breast cancer: are we doing better?</title><author>Fallowfield, Lesley ; Jenkins, Valerie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c354t-f91657f3ec664ab79ac98a008bd3579e6a0c9a4f40fb05ea27f9ba4759944e413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Affective Symptoms - etiology</topic><topic>Antineoplastic Agents, Hormonal - adverse effects</topic><topic>Antineoplastic Combined Chemotherapy Protocols - adverse effects</topic><topic>Anxiety - etiology</topic><topic>Breast cancer</topic><topic>Breast Neoplasms - pathology</topic><topic>Breast Neoplasms - psychology</topic><topic>Breast Neoplasms - therapy</topic><topic>Case-Control Studies</topic><topic>Cognitive Dysfunction - etiology</topic><topic>Communication</topic><topic>Depression - etiology</topic><topic>Dyspareunia - etiology</topic><topic>Evidence-Based Medicine</topic><topic>Fatigue - etiology</topic><topic>Female</topic><topic>Health Status</topic><topic>Humans</topic><topic>Iatrogenic Disease</topic><topic>Intervention</topic><topic>Lymphedema - etiology</topic><topic>Medical treatment</topic><topic>Neoplasm Recurrence, Local - psychology</topic><topic>Physician-Patient Relations</topic><topic>Practice Guidelines as Topic</topic><topic>Quality Indicators, Health Care</topic><topic>Quality of Life</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Risk Assessment</topic><topic>Stress, Psychological - epidemiology</topic><topic>Stress, Psychological - etiology</topic><topic>Stress, Psychological - prevention & control</topic><topic>Stress, Psychological - therapy</topic><topic>Survivors - psychology</topic><topic>Survivors - statistics & numerical data</topic><topic>Vasomotor System - drug effects</topic><topic>Vasomotor System - physiopathology</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fallowfield, Lesley</creatorcontrib><creatorcontrib>Jenkins, Valerie</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>JNCI : Journal of the National Cancer Institute</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fallowfield, Lesley</au><au>Jenkins, Valerie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Psychosocial/survivorship issues in breast cancer: are we doing better?</atitle><jtitle>JNCI : Journal of the National Cancer Institute</jtitle><addtitle>J Natl Cancer Inst</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>107</volume><issue>1</issue><spage>335</spage><epage>dju335</epage><pages>335-dju335</pages><issn>0027-8874</issn><eissn>1460-2105</eissn><coden>JNCIEQ</coden><abstract>Modern breast cancer treatment offers many women greater prospects of cure or lengthier, good quality survival than was possible in the past. Advances include improved diagnostic and staging procedures, sophisticated onco-plastic surgery, enhanced radiotherapy techniques, and targeted systemic therapies. Much more attention has also been paid to cancer care delivery and access to specialist nurses, counsellors, support groups, and services provided by breast cancer charities. However, there are some concerns that these considerable improvements in treatment delivery and clinical outcomes have not led to similar benefits in the psychosocial, functional, and sexual well-being of women. The impact that non-life threatening, long-term iatrogenic harms of otherwise efficacious anticancer treatments has on patients is often overlooked; this is in part because of the emphasis given to physician-reported safety data in trials and the general exclusion of patient-reported outcomes (PROs). A failure to utilise reliable PRO measures has meant that some problems are underreported, which consequently has hampered much-needed research into ameliorative interventions. Systematic monitoring of quality of life-threatening side effects would permit early implementation of effective interventions and enhance long-term survivorship. Some examples of the pervasive difficulties that continue to affect survivors and evidence that certain interventions might help are provided in this commentary.</abstract><cop>United States</cop><pub>Oxford Publishing Limited (England)</pub><pmid>25432407</pmid><doi>10.1093/jnci/dju335</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Affective Symptoms - etiology Antineoplastic Agents, Hormonal - adverse effects Antineoplastic Combined Chemotherapy Protocols - adverse effects Anxiety - etiology Breast cancer Breast Neoplasms - pathology Breast Neoplasms - psychology Breast Neoplasms - therapy Case-Control Studies Cognitive Dysfunction - etiology Communication Depression - etiology Dyspareunia - etiology Evidence-Based Medicine Fatigue - etiology Female Health Status Humans Iatrogenic Disease Intervention Lymphedema - etiology Medical treatment Neoplasm Recurrence, Local - psychology Physician-Patient Relations Practice Guidelines as Topic Quality Indicators, Health Care Quality of Life Randomized Controlled Trials as Topic Risk Assessment Stress, Psychological - epidemiology Stress, Psychological - etiology Stress, Psychological - prevention & control Stress, Psychological - therapy Survivors - psychology Survivors - statistics & numerical data Vasomotor System - drug effects Vasomotor System - physiopathology Womens health |
title | Psychosocial/survivorship issues in breast cancer: are we doing better? |
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