Opiates and infection
This review on the effects of opiate use on infectious diseases discusses the complete spectrum of infections in the opiate user, including those of the lung, the GI tract, the skin, the skeletal system, and the CNS. There is both increased prevalence and increased severity of bacterial and viral in...
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Veröffentlicht in: | Journal of neuroimmunology 1998-03, Vol.83 (1-2), p.4-18 |
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creator | Risdahl, Jack M Khanna, Kristen V Peterson, Phillip K Molitor, Thomas W |
description | This review on the effects of opiate use on infectious diseases discusses the complete spectrum of infections in the opiate user, including those of the lung, the GI tract, the skin, the skeletal system, and the CNS. There is both increased prevalence and increased severity of bacterial and viral infections in injection drug users with the outcome of increased morbidity and mortality. The experimental administration of opiates has lead to a greater understanding of the effects on susceptibility to and progression of infectious diseases. Animal models of opiate dependence and infection are reviewed with specific attention to cases in which the opiate-mediated effects are harmful and in which cases they are beneficial. |
doi_str_mv | 10.1016/S0165-5728(97)00216-6 |
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There is both increased prevalence and increased severity of bacterial and viral infections in injection drug users with the outcome of increased morbidity and mortality. The experimental administration of opiates has lead to a greater understanding of the effects on susceptibility to and progression of infectious diseases. Animal models of opiate dependence and infection are reviewed with specific attention to cases in which the opiate-mediated effects are harmful and in which cases they are beneficial.</description><identifier>ISSN: 0165-5728</identifier><identifier>EISSN: 1872-8421</identifier><identifier>DOI: 10.1016/S0165-5728(97)00216-6</identifier><identifier>PMID: 9610668</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Bacteria ; Communicable Diseases - epidemiology ; Communicable Diseases - immunology ; Communicable Diseases - transmission ; Drugs-of-abuse ; Humans ; Immunosuppression ; Morphine ; Opiates ; Opioid-Related Disorders - epidemiology ; Opioid-Related Disorders - microbiology ; Opioid-Related Disorders - virology ; Risk Factors ; Virus ; Virus Diseases - epidemiology ; Virus Diseases - immunology ; Virus Diseases - transmission</subject><ispartof>Journal of neuroimmunology, 1998-03, Vol.83 (1-2), p.4-18</ispartof><rights>1998 Elsevier Science B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c416t-b4366c11f5785769d4676c1a6c5babe9e77e351d1b3dd8d8242eb1d74049370b3</citedby><cites>FETCH-LOGICAL-c416t-b4366c11f5785769d4676c1a6c5babe9e77e351d1b3dd8d8242eb1d74049370b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0165-5728(97)00216-6$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9610668$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Risdahl, Jack M</creatorcontrib><creatorcontrib>Khanna, Kristen V</creatorcontrib><creatorcontrib>Peterson, Phillip K</creatorcontrib><creatorcontrib>Molitor, Thomas W</creatorcontrib><title>Opiates and infection</title><title>Journal of neuroimmunology</title><addtitle>J Neuroimmunol</addtitle><description>This review on the effects of opiate use on infectious diseases discusses the complete spectrum of infections in the opiate user, including those of the lung, the GI tract, the skin, the skeletal system, and the CNS. 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Animal models of opiate dependence and infection are reviewed with specific attention to cases in which the opiate-mediated effects are harmful and in which cases they are beneficial.</description><subject>Bacteria</subject><subject>Communicable Diseases - epidemiology</subject><subject>Communicable Diseases - immunology</subject><subject>Communicable Diseases - transmission</subject><subject>Drugs-of-abuse</subject><subject>Humans</subject><subject>Immunosuppression</subject><subject>Morphine</subject><subject>Opiates</subject><subject>Opioid-Related Disorders - epidemiology</subject><subject>Opioid-Related Disorders - microbiology</subject><subject>Opioid-Related Disorders - virology</subject><subject>Risk Factors</subject><subject>Virus</subject><subject>Virus Diseases - epidemiology</subject><subject>Virus Diseases - immunology</subject><subject>Virus Diseases - transmission</subject><issn>0165-5728</issn><issn>1872-8421</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUE1LAzEQDaLUWj16LPQkeljNZJPJ5iSl-AWFHtRz2CSzEGl362Yr-O_dftCrlxmG99483mNsDPweOODDez9UprQobo2-41wAZnjChlBokRVSwCkbHinn7CKlL85B5dIM2MAgcMRiyK4X61h2lCZlHSaxrsh3sakv2VlVLhNdHfaIfT4_fcxes_ni5W02nWdeAnaZkzmiB6iULpRGEyTq_i7RK1c6MqQ15QoCuDyEIhRCCnIQtOTS5Jq7fMRu9n_XbfO9odTZVUyelsuypmaTLKAwUmLeE9We6NsmpZYqu27jqmx_LXC7rcPu6rDbrNZou6vDYq8bHww2bkXhqDrk7_HHPU59yp9IrU0-Uu0pxLavwoYm_uPwB_ETbJo</recordid><startdate>19980315</startdate><enddate>19980315</enddate><creator>Risdahl, Jack M</creator><creator>Khanna, Kristen V</creator><creator>Peterson, Phillip K</creator><creator>Molitor, Thomas W</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope></search><sort><creationdate>19980315</creationdate><title>Opiates and infection</title><author>Risdahl, Jack M ; Khanna, Kristen V ; Peterson, Phillip K ; Molitor, Thomas W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c416t-b4366c11f5785769d4676c1a6c5babe9e77e351d1b3dd8d8242eb1d74049370b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Bacteria</topic><topic>Communicable Diseases - epidemiology</topic><topic>Communicable Diseases - immunology</topic><topic>Communicable Diseases - transmission</topic><topic>Drugs-of-abuse</topic><topic>Humans</topic><topic>Immunosuppression</topic><topic>Morphine</topic><topic>Opiates</topic><topic>Opioid-Related Disorders - epidemiology</topic><topic>Opioid-Related Disorders - microbiology</topic><topic>Opioid-Related Disorders - virology</topic><topic>Risk Factors</topic><topic>Virus</topic><topic>Virus Diseases - epidemiology</topic><topic>Virus Diseases - immunology</topic><topic>Virus Diseases - transmission</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Risdahl, Jack M</creatorcontrib><creatorcontrib>Khanna, Kristen V</creatorcontrib><creatorcontrib>Peterson, Phillip K</creatorcontrib><creatorcontrib>Molitor, Thomas W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Journal of neuroimmunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Risdahl, Jack M</au><au>Khanna, Kristen V</au><au>Peterson, Phillip K</au><au>Molitor, Thomas W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Opiates and infection</atitle><jtitle>Journal of neuroimmunology</jtitle><addtitle>J Neuroimmunol</addtitle><date>1998-03-15</date><risdate>1998</risdate><volume>83</volume><issue>1-2</issue><spage>4</spage><epage>18</epage><pages>4-18</pages><issn>0165-5728</issn><eissn>1872-8421</eissn><abstract>This review on the effects of opiate use on infectious diseases discusses the complete spectrum of infections in the opiate user, including those of the lung, the GI tract, the skin, the skeletal system, and the CNS. 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subjects | Bacteria Communicable Diseases - epidemiology Communicable Diseases - immunology Communicable Diseases - transmission Drugs-of-abuse Humans Immunosuppression Morphine Opiates Opioid-Related Disorders - epidemiology Opioid-Related Disorders - microbiology Opioid-Related Disorders - virology Risk Factors Virus Virus Diseases - epidemiology Virus Diseases - immunology Virus Diseases - transmission |
title | Opiates and infection |
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