Opiates and infection

This review on the effects of opiate use on infectious diseases discusses the complete spectrum of infections in the opiate user, including those of the lung, the GI tract, the skin, the skeletal system, and the CNS. There is both increased prevalence and increased severity of bacterial and viral in...

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Veröffentlicht in:Journal of neuroimmunology 1998-03, Vol.83 (1-2), p.4-18
Hauptverfasser: Risdahl, Jack M, Khanna, Kristen V, Peterson, Phillip K, Molitor, Thomas W
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container_issue 1-2
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container_title Journal of neuroimmunology
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creator Risdahl, Jack M
Khanna, Kristen V
Peterson, Phillip K
Molitor, Thomas W
description This review on the effects of opiate use on infectious diseases discusses the complete spectrum of infections in the opiate user, including those of the lung, the GI tract, the skin, the skeletal system, and the CNS. There is both increased prevalence and increased severity of bacterial and viral infections in injection drug users with the outcome of increased morbidity and mortality. The experimental administration of opiates has lead to a greater understanding of the effects on susceptibility to and progression of infectious diseases. Animal models of opiate dependence and infection are reviewed with specific attention to cases in which the opiate-mediated effects are harmful and in which cases they are beneficial.
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subjects Bacteria
Communicable Diseases - epidemiology
Communicable Diseases - immunology
Communicable Diseases - transmission
Drugs-of-abuse
Humans
Immunosuppression
Morphine
Opiates
Opioid-Related Disorders - epidemiology
Opioid-Related Disorders - microbiology
Opioid-Related Disorders - virology
Risk Factors
Virus
Virus Diseases - epidemiology
Virus Diseases - immunology
Virus Diseases - transmission
title Opiates and infection
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