Chiral analysis of amino acid neurotransmitters and neuromodulators in mouse brain by CE-LIF

Chiral CE method has been developed for quantitative determination of d‐amino acid modulators of NMDA glutamate receptor; d‐serine and d‐aspartate along with l‐glutamate and l‐aspartate in biological samples. These ligands are suggested to be involved in regulation of NMDA receptor related brain fun...

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Veröffentlicht in:	Electrophoresis 2014-10, Vol.35 (19), p.2870-2876
Hauptverfasser:	Jakó, Tamás, Szabó, Eszter, Tábi, Tamás, Zachar, Gergely, Csillag, András, Szökő, Éva
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Amino acids Analytical chemistry Animals Brain Brain Chemistry CE-LIF Chiral separation Electrophoresis Electrophoresis, Capillary - methods Excitatory Amino Acids - analysis Excitatory Amino Acids - chemistry Linear Models Male Mice Mice, Inbred C57BL Neurotransmitters NMDA receptor modulators Receptors Reproducibility of Results Sensitivity and Specificity Stereoisomerism
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