Modelling amyloid fibril formation kinetics: mechanisms of nucleation and growth

Amyloid and amyloid-like fibrils are self-assembling protein nanostructures, of interest for their robust material properties and inherent biological compatibility as well as their putative role in a number of debilitating mammalian disorders. Understanding fibril formation is essential to the devel...

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Veröffentlicht in:	Journal of physics. Condensed matter 2013-09, Vol.25 (37), p.373101-20
Hauptverfasser:	Gillam, J E, MacPhee, C E
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid - chemistry Analytical, structural and metabolic biochemistry Animals Assembly Biocatalysis Biological and medical sciences Condensed matter Disorders Formations Fundamental and applied biological sciences. Psychology General aspects, investigation methods Humans Kinetics Mathematical models Models, Molecular Nucleation Protein Multimerization Proteins Strategy
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