Chromatographic analysis of some drugs employed in erectile dysfunction therapy: Qualitative and quantitative studies using calixarene stationary phase

In this study, the effect of change in chromatographic process variables on the retention behavior of four drugs employed in erectile dysfunction therapy on a calixarene stationary phase is described. Three of these drugs are known to treat erectile dysfunction, namely, sildenafil citrate, tadalafil...

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Veröffentlicht in:	Journal of separation science 2014-10, Vol.37 (20), p.2814-2824
Hauptverfasser:	Hashem, Hisham, Ibrahim, Adel Ehab, Elhenawee, Magda
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apomorphine - analysis Apomorphine - therapeutic use Biological and medical sciences Buffers Calixarene column Calixarenes Calixarenes - chemistry Carbolines - analysis Carbolines - therapeutic use Chromatographic variables Chromatography Chromatography, High Pressure Liquid - methods Citrates Drugs Erectile dysfunction Erectile Dysfunction - drug therapy General pharmacology High-performance liquid chromatography Humans Hydrochlorides Hydrogen-Ion Concentration Limit of Detection Male Medical sciences Pharmaceutical Preparations - chemistry Pharmaceuticals Pharmacology Pharmacology. Drug treatments Piperazines - analysis Piperazines - therapeutic use Purines - analysis Purines - therapeutic use Reproducibility of Results Sexual disorders Sildenafil Citrate Sulfonamides - analysis Sulfonamides - therapeutic use Tadalafil Therapy
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