Precision and reliability of 5 platelet function tests in healthy volunteers and donors on daily antiplatelet agent therapy

Anticoagulation protocols used during mechanical circulatory support call for titration of antiplatelet agents. We compared the precision and reliability of 5 platelet function tests in healthy volunteers and donors on daily antiplatelet therapy to distinguish their efficacy for titrating antiplatel...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2014-12, Vol.60 (12), p.1524-1531
Hauptverfasser:	Karon, Brad S, Tolan, Nicole V, Koch, Christopher D, Wockenfus, Amy M, Miller, Randall S, Lingineni, Ravi K, Pruthi, Rajiv K, Chen, Dong, Jaffe, Allan S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Adenosine diphosphate Anticoagulants Arachidonic Acid - pharmacology Aspirin Aspirin - administration & dosage Aspirin - therapeutic use Blood platelets Clopidogrel Female Healthy Volunteers Humans Impedance Light transmission Male Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - administration & dosage Platelet Aggregation Inhibitors - therapeutic use Platelet Function Tests - standards Reproducibility of Results Sensitivity and Specificity Thromboembolism Thrombosis Ticlopidine - administration & dosage Ticlopidine - analogs & derivatives Ticlopidine - therapeutic use
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