Cytotoxic T-lymphocyte responses in cattle infected with bovine viral diarrhea virus

A system for a reproducible in vitro restimulation of bovine viral diarrhea virus (BVDV)-specific cytotoxic T-cells (CTL) was developed. Lymphocyte cultures of BVDV-immunised cattle were stimulated with infectious BVDV isolate PT810 and recombinant bovine interleukin-2 for 12 to 25 days. A specific...

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Veröffentlicht in:	Veterinary microbiology 1997-10, Vol.58 (1), p.9-22
Hauptverfasser:	Beer, M., Wolf, G., Pichler, J., Wolfmeyer, A., Kaaden, O.-R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - analysis Biological and medical sciences Bovine viral diarrhea virus Bovine Virus Diarrhea-Mucosal Disease - blood Bovine Virus Diarrhea-Mucosal Disease - immunology Bovine Virus Diarrhea-Mucosal Disease - pathology Cattle Cattle-viruses Cell mediated immunity Cytotoxic T-cells Cytotoxicity Tests, Immunologic - veterinary Diarrhea Viruses, Bovine Viral - immunology Flow Cytometry - veterinary Fluorescent Antibody Technique, Indirect - veterinary Fundamental and applied biological sciences. Psychology Histocompatibility Antigens Class II - blood Histocompatibility Antigens Class II - immunology Immunity, Cellular Interleukin-2 - immunology Lymphocyte Activation Microbiology Neutralization Tests - veterinary Recombinant Proteins - immunology T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - virology Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Viral Vaccines - immunology Virology
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