Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations

Tumor-infiltrating inflammatory cells comprise a major part of the stromal microenvironment and support cancer progression by multiple mechanisms. High numbers of tumor myeloid cells correlate with poor prognosis in breast cancer and are coupled with the angiogenic switch and malignant progression....

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2014-11, Vol.111 (47), p.E5086-E5095
Hauptverfasser: Lohela, Marja, Casbon, Amy-Jo, Olow, Aleksandra, Bonham, Lynn, Branstetter, Daniel, Weng, Ning, Smith, Jeffrey, Werb, Zena
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Sprache:eng
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