Mice Deficient in the alpha 7 Neuronal Nicotinic Acetylcholine Receptor Lack alpha -Bungarotoxin Binding Sites and Hippocampal Fast Nicotinic Currents

The alpha 7 subunit of the neuronal nicotinic acetylcholine receptor (nAChR) is abundantly expressed in hippocampus and is implicated in modulating neurotransmitter release and in binding alpha -bungarotoxin ( alpha -BGT). A null mutation for the alpha 7 subunit was prepared by deleting the last thr...

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Veröffentlicht in:The Journal of neuroscience 1997-12, Vol.17 (23), p.9165-9171
Hauptverfasser: Orr-Urtreger, Avi, Goldner, Finn M, Saeki, Mayuko, Lorenzo, Isabel, Goldberg, Leah, De Biasi, Mariella, Dani, John A, Patrick, James W, Beaudet, Arthur L
Format: Artikel
Sprache:eng
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