Optimization a large-scale chromatography for biotechnological applications

An economic evaluation of a chromatographic separation is discussed. The effects of particle size, cycle time, solvent, and column costs are analyzed. With small particles (< 20 mu m), the cost of the packing can be as much as 99% of the total cost of the process, whereas with large particles (&g...

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Veröffentlicht in:Applied biochemistry and biotechnology 1992-03, Vol.34-35 (1), p.49-59
Hauptverfasser: PESKIN, A. P, RUDGE, S. R
Format: Artikel
Sprache:eng
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