Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: A mechanistic study

•The present study was to investigate the synergistic effects of QE and QA on STZ-induced diabetic rats.•Combination dose of QE and QA prevents the hyperglycaemia, oxidative stress and lipid accumulation in diabetic rats.•QE and QA treatment also inhibited the Bax expression and increased the Bcl-2...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Food and chemical toxicology 2014-09, Vol.71, p.183-196
Hauptverfasser:	Arya, Aditya, Jamil Al-Obaidi, Mazen M, Shahid, Nayiar, Bin Noordin, Mohamed Ibrahim, Looi, Chung Yeng, Wong, Won Fen, Khaing, Si Lay, Mustafa, Mohd Rais
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antineoplastic agents Antioxidants - metabolism Biological and medical sciences Chemotherapy Diabetes mellitus Diabetes. Impaired glucose tolerance Drug Synergism Endocrine pancreas. Apud cells (diseases) Endocrinopathies Enzymes - blood Etiopathogenesis. Screening. Investigations. Target tissue resistance Food toxicology Kidney - drug effects Kidney - pathology Liver - drug effects Liver - pathology Male Malondialdehyde - metabolism Medical sciences Pancreas - drug effects Pancreas - pathology Pharmacology. Drug treatments Quercetin Quercetin - pharmacology Quinic acid Quinic Acid - pharmacology Rats Rats, Sprague-Dawley Streptozocin Streptozotocin Synergistic effect Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!