Toxicologic evaluation of Dichrostachys glomerata extract: Subchronic study in rats and genotoxicity tests

•Subchronic toxicity and genotoxicity of Dichrostachys glomerata extract was investigated.•No adverse effects of D. glomerata extract were noted in rats at doses up to 2500mg/kg/day.•Dichrostachys glomerata extract was not genotoxic as evaluated by in vitro and in vivo studies.•The No Observed-Adver...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Food and chemical toxicology 2014-07, Vol.69, p.120-131
Hauptverfasser:	Kothari, Shil C., Shivarudraiah, Prasad, Venkataramaiah, Suresh Babu, Gavara, Swapna, Arumugam, Shri Natrajan, Soni, Madhu G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Body Weight - drug effects Cameroon Chromosome Aberrations Dichrostachys Dichrostachys glomerata Dietary supplement Eating - drug effects Fabaceae - chemistry Female Food toxicology Male Medical sciences Micronucleus Tests Mutagenicity Tests - methods No-Observed-Adverse-Effect Level Organ Size - drug effects Plant Extracts - toxicity Rats, Sprague-Dawley Safety Salmonella typhimurium - drug effects Salmonella typhimurium - genetics Toxicity Toxicity Tests, Subchronic - methods Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!