Uncoupling protein 2 −866G/A and uncoupling protein 3 −55C/T polymorphisms in young South African Indian coronary artery disease patients

Uncoupling proteins (UCPs) 2 and 3 play an important role in the regulation of oxidative stress which contributes to chronic inflammation. Promoter polymorphisms of these genes have been linked to chronic diseases including heart disease and type II diabetes mellitus in several populations. This is...

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Veröffentlicht in:	Gene 2013-07, Vol.524 (2), p.79-83
Hauptverfasser:	Phulukdaree, Alisa, Moodley, Devapregasan, Khan, Sajidah, Chuturgoon, Anil A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult African Continental Ancestry Group - genetics Blood Glucose - analysis Case-Control Studies chronic diseases Coronary artery disease Coronary Artery Disease - ethnology Coronary Artery Disease - genetics fasting Gene Frequency genes Genetic Association Studies Genotype glucose Glycated Hemoglobin A - analysis heterozygosity homozygosity Humans India - ethnology inflammation Ion Channels - genetics Male males Middle Aged Mitochondrial Proteins - genetics noninsulin-dependent diabetes mellitus Odds Ratio oxidative stress patients Polymerase Chain Reaction Polymorphism Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide Promoter Regions, Genetic proteins restriction fragment length polymorphism risk Risk Factors South Africa - epidemiology triacylglycerols Triglycerides - analysis Uncoupling protein Uncoupling Protein 2 Uncoupling Protein 3 Young Adult
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