Effects of the human antiepileptic drug carbamazepine on the behavior, biomarkers, and heat shock proteins in the Asian clam Corbicula fluminea

•The siphoning behavior of the clam was inhibited by CBZ.•CBZ exposure induced oxidative effects to the clam.•The expressions of five heat shock proteins genes were altered by CBZ.•The protein levels of Hsp70 were up-regulated by CBZ. Carbamazepine (CBZ), an anticonvulsant and mood-stabilizing pharm...

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Veröffentlicht in:	Aquatic toxicology 2014-10, Vol.155, p.1-8
Hauptverfasser:	Chen, Huihui, Zha, Jinmiao, Liang, Xuefang, Li, Jiasu, Wang, Zijian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal, plant and microbial ecology Animals Anticonvulsants - administration & dosage Anticonvulsants - toxicity Antioxidant enzymes Applied ecology Behavior, Animal - drug effects Biological and medical sciences Biomarkers Carbamazepine Carbamazepine - administration & dosage Carbamazepine - toxicity Corbicula - drug effects Corbicula - physiology Corbicula fluminea Dose-Response Relationship, Drug Ecotoxicology, biological effects of pollution Effects of pollution and side effects of pesticides on protozoa and invertebrates Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects Gills - drug effects Heat shock proteins Heat-Shock Proteins - genetics Heat-Shock Proteins - metabolism Siphoning behavior Water Pollutants, Chemical - administration & dosage Water Pollutants, Chemical - toxicity
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