Heterogeneous nuclear ribonucleoprotein A1 in health and neurodegenerative disease: From structural insights to post-transcriptional regulatory roles

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a family of conserved nuclear proteins that associate with nascent RNA polymerase II transcripts to yield hnRNP particles, playing key roles in mRNA metabolism, DNA-related functions and microRNA biogenesis. HnRNPs accompany transcripts from stag...

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Veröffentlicht in:	Molecular and cellular neuroscience 2013-09, Vol.56, p.436-446
Hauptverfasser:	Bekenstein, Uriya, Soreq, Hermona
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Binding Sites Heterogeneous Nuclear Ribonucleoprotein A1 Heterogeneous-Nuclear Ribonucleoprotein Group A-B - chemistry Heterogeneous-Nuclear Ribonucleoprotein Group A-B - genetics Heterogeneous-Nuclear Ribonucleoprotein Group A-B - metabolism Human T-lymphotropic virus 1 Humans Molecular Sequence Data Neurodegenerative Diseases - genetics Neurodegenerative Diseases - metabolism RNA - metabolism RNA Processing, Post-Transcriptional
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