CXCR-7 receptor promotes SDF-1α-induced migration of bone marrow mesenchymal stem cells in the transient cerebral ischemia/reperfusion rat hippocampus

Abstract The stromal cell-derived factor 1/C-X-C chemokine receptor type 4 (SDF-1/CXCR-4) axis plays an important role during stem cell recruitment. SDF-1 can also bind the more recently described CXCR-7 receptor, but effects of SDF-1/CXCR-7 signaling on stem cell migrating to ischemic brain injury...

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Veröffentlicht in:	Brain research 2014-08, Vol.1575, p.78-86
Hauptverfasser:	Wang, Yulan, Fu, Wei, Zhang, Shichun, He, Xiaomei, Liu, Zhi’an, Gao, Diansuai, Xu, Tiejun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone marrow mesenchymal stem cell C-X-C chemokine receptor 7 Cell Movement Chemokine CXCL12 - metabolism Fundamental and applied biological sciences. Psychology Hippocampus Hippocampus - metabolism Ischemia/reperfusion Ischemic Attack, Transient - metabolism Male Medical sciences Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells - metabolism Migration Neurology Rats Rats, Sprague-Dawley Receptors, CXCR - metabolism Receptors, CXCR4 - metabolism Reperfusion Injury - metabolism Stromal cell-derived factor-1α Vascular diseases and vascular malformations of the nervous system Vertebrates: nervous system and sense organs
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