Bee venom phospholipase A2‐specific T cell clones from human allergic and non‐allergic individuals: cytokine patterns change in response to the antigen concentration

Protein antigens with both allergenic and immunoprotective properties represent appropriate molecules to study IgE and IgG regulation. We have established a panel of T cell clones specific to bee venom phospholipase A2 (PLA) from human individuals allergic, hyposensitized or immune (protected) to be...

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Veröffentlicht in:	European journal of immunology 1992-06, Vol.22 (6), p.1357-1363
Hauptverfasser:	Carballido, José M., Carballido‐Perrig, Nicole, Terres, GeróNimo, Heusser, Christoph H., Blaser, Kurt
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Apis Bee Venoms - immunology Biological and medical sciences Cell Division - immunology Clone Cells Cytokines - biosynthesis Dose-Response Relationship, Immunologic Fundamental and applied biological sciences. Psychology Fundamental immunology Gene Expression Regulation Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis HLA-D Antigens - analysis Humans Immunobiology Immunophenotyping Insect Bites and Stings - immunology Interferon-gamma - biosynthesis Interleukin-4 - biosynthesis Interleukin-5 - biosynthesis Lymphokines, interleukins ( function, expression) Lymphotoxin-alpha - biosynthesis Phospholipases A - immunology Phospholipases A2 Regulatory factors and their cellular receptors T-Lymphocytes - metabolism Tumor Necrosis Factor-alpha - biosynthesis
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