Evaluation of the Moisture Prediction Capability of Near-Infrared and Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy Using Superdisintegrants as Model Compounds

The superdisintegrants (SDs) moisture content measurement by near-infrared (NIR) spectroscopy and attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy has been evaluated against thermogravimetric analysis as a reference method. SDs with varying moisture content were used t...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2014-12, Vol.103 (12), p.4012-4020
Hauptverfasser:	Uppaluri, Sai G., Bompelliwar, Sai K., Johnson, Paul R., Gupta, Mali R., Al-Achi, Antoine, Stagner, William C., Haware, Rahul V.
Format:	Artikel
Sprache:	eng
Schlagworte:	ATR-FTIR spectroscopy Calibration Least-Squares Analysis material science, moisture content mathematical model multivariate analysis (MVA) NIR spectroscopy partial least square regression (PLS) principal component analysis process analytical technology Spectroscopy, Fourier Transform Infrared - methods Spectroscopy, Near-Infrared - methods superdisintegrants (SDs) Water - chemistry
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